Mineralocorticoid receptor-associated mechanisms in diabetic kidney disease and clinical significance of mineralocorticoid receptor antagonists

CW Mende, R Samarakoon, PJ Higgins - American Journal of …, 2023 - karger.com
Background: Diabetic kidney disease (DKD) is a common disorder with multiple serious
clinical implications, including an increased risk of end-stage kidney disease (ESKD) …

Overview of the safety, efficiency, and potential mechanisms of finerenone for diabetic kidney diseases

W Chen, L Zheng, J Wang, Y Lin, T Zhou - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a common disorder with numerous severe clinical
implications. Due to a high level of fibrosis and inflammation that contributes to renal and …

Chronic High-Salt Diet Activates Tumor-Initiating Stem Cells Leading to Breast Cancer Proliferation

L Tucker, U Ali, R Zent, DA Lannigan, JC Rathmell… - Cells, 2024 - mdpi.com
Several chronic inflammatory diseases have been linked to high-salt (HS) diets. Chronic
inflammation is an established causative hallmark of cancer. However, a direct role of HS …

Mitochondrial damage and hypertension: another dark side of sodium excess

B Afsar, RE Afsar - Current Nutrition Reports, 2023 - Springer
Abstract Purpose of Review Essential or primary hypertension (HT) is a worldwide health
problem with no definitive cure. Although the exact pathogenesis of HT is not known, genetic …

Dietary sodium and human health

DA Jaques, B Ponte - Nutrients, 2023 - mdpi.com
Sodium, contained in dietary salt, is essential to human life. For millions of years, our
ancestors did not add salt to their diet but rather relied on sodium naturally present in …

[HTML][HTML] Salt content of prepacked cereal-based products and their potential contribution to salt intake of the Italian adult population: Results from a simulation study

G Vici, A Rosi, D Angelino, V Polzonetti… - Nutrition, Metabolism …, 2024 - Elsevier
Background and aims High sodium intake is one of the main risk factors for
noncommunicable diseases, and its consumption should be reduced. This study aimed to …

The reduction of salt in different cheese categories: recent advances and future challenges

F Tidona, M Zago, D Carminati, G Giraffa - Frontiers in Nutrition, 2022 - frontiersin.org
Public awareness about excessive sodium intake and nutrition claims related to salt content
entail the need for food industries to carefully reconsider the composition and processing of …

Assessment of the effects of salt and Salicornia herbacea L. on physiochemical, nutritional, and quality parameters for extending the shelf-life of semi-dried mullets …

HG Jo, R Chilakala, MJ Kim, YS Sin, KS Lee… - Foods, 2022 - mdpi.com
Mullet, a coastal fish species, is commonly used as a salted dried fish in many countries,
including Korea, Japan, and the southeastern United States. The purpose of this …

Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective US cohort study, systematic review, and …

L Gan, B Zhao, M Inoue-Choi, LM Liao, BI Graubard… - BMC medicine, 2024 - Springer
Background The impact of sodium intake on cardiovascular disease (CVD) health and
mortality has been studied for decades, including the well-established association with …

Integrated analysis of miRNA and mRNA regulation network in hypertension

W Xu, F Liu, Q Li, L Li, X Liu - Biochemical Genetics, 2023 - Springer
Hypertension is the most common chronic disease. Early diagnosis is helpful for early
medical intervention. The miRNAs and the messenger RNAs (mRNAs) network may be …