Molecular in vivo neuroimaging techniques can be used to measure regional changes in
endogenous neurotransmitters, evoked by challenges that alter synaptic neurotransmitter …

Neurotransmitter switching is a form of brain plasticity in which an environmental stimulus
causes neurons to replace one neurotransmitter with another, often resulting in changes in …

Background Internet gaming disorder is an increasing problem worldwide, resulting in
critical academic, social, and occupational impairment. However, the neurobiological …

Methylphenidate (MP) and amphetamine (AMP) are first‐line treatments for attention‐deficit
hyperactivity disorder. Although both drugs have similar therapeutic potencies, the …

Abstract Although abnormal serotonin (5‐HT) function is implicated in a range of mental
disorders, there is currently no method to directly assess 5‐HT synaptic levels in the living …

Drugs acting on the 5-HT 1A receptor are used in the treatment of depression, generalized
anxiety disorder, and schizophrenia. This study investigated 5-HT 1A receptor occupancy by …

4, 2′-(Methoxyphenyl)-1-[2′-(N-2 ″-pyridinyl)-p-fluorobenzamido] ethylpiperazine (18F-
MPPF) is a radiotracer used in clinical PET studies for the visualization of serotonin-1A (5 …

PET has deep roots in neuroscience stemming from its first application in brain tumor and
brain metabolism imaging. PET emerged over the past few decades and continues to play a …

Dopaminergic signaling influences physical activity. Notably impaired D2 receptor (D2R)
function has been associated with decreased voluntary physical activity. Most animal …

The aim of the present study was to develop an experimental paradigm for the study of
serotonergic neurotransmission in humans using positron emission tomography and the 5 …