After being a neglected and poorly-understood disorder for many years, there has been a
recent explosion of data regarding the complex pathogenesis of myelodysplastic syndromes …

Simple Summary Myelodysplastic syndrome (MDS) is a type of blood cancer that mostly
affects older individuals. Invasive tests to obtain bone samples are used to diagnose MDS …

After allogeneic stem cell transplantation, graft-versus-host disease (GvHD) occurs through
recognition of histocompatibility mismatches by donor T lymphocytes. The same mechanism …

Relapse is a devastating event for patients with hematologic cancers treated with
hematopoietic stem cell transplantation. In most situations, relapse treatment options are …

Abstract Treatment options for older patients with advanced myelodysplastic syndromes
(MDS) or acute myeloid leukemia (AML) are limited and the prognosis remains poor, thereby …

Several classification and scoring systems have been developed in myelodysplastic
syndromes (MDS to predict the risk of progression to acute myeloid leukemia and survival …

Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract arising in
individuals with genetic predisposing factors and abnormalities of the immune system …

Objective The purposes of this study were to assess the efficacy of allogeneic hematopoietic
stem cell transplantation (HSCT) for acute leukemia (AL) and analyze the factors affecting …

Although new agents have been approved for the treatment of MDS, the only curative
approach is allogeneic hematopoietic stem cell transplantation (HSCT) and thus, in …

The work of Fraser et al. represents an important step in our understanding of the complex
interplay between erythroid and macrophage biology in the regulation of red cell production …