Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

The rising crisis of illicit fentanyl use, overdose, and potential therapeutic strategies

Y Han, W Yan, Y Zheng, MZ Khan, K Yuan… - Translational psychiatry, 2019 - nature.com
Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

Management of pharmaceutical and recreational drug poisoning

B Mégarbane, M Oberlin, JC Alvarez, F Balen… - Annals of intensive …, 2020 - Springer
Background Poisoning is one of the leading causes of admission to the emergency
department and intensive care unit. A large number of epidemiological changes have …

An update on the implications of new psychoactive substances in public health

AY Simão, M Antunes, E Cabral, P Oliveira… - International journal of …, 2022 - mdpi.com
The emergence of new psychoactive substances has earned a great deal of attention, and
several reports of acute poisoning and deaths have been issued involving, for instance …

Alkaloids in contemporary drug discovery to meet global disease needs

S Daley, GA Cordell - Molecules, 2021 - mdpi.com
An overview is presented of the well-established role of alkaloids in drug discovery, the
application of more sustainable chemicals, and biological approaches, and the …

[图书][B] Fundamentals of analytical toxicology

RJ Flanagan, AA Taylor, ID Watson, R Whelpton - 2008 - books.google.com
The analytical toxicologist may be required to detect, identify, and in many cases measure a
wide variety of compounds in samples from almost any part of the body or in related …

Reports of adverse events associated with use of novel psychoactive substances, 2017–2020: a review

ALA Mohr, BK Logan, MF Fogarty… - Journal of Analytical …, 2022 - academic.oup.com
An important role of modern forensic and clinical toxicologists is to monitor the adverse
events of novel psychoactive substances (NPS). Following a prior review from 2013 to 2016 …

U-47700 and its analogs: non-fentanyl synthetic opioids impacting the recreational drug market

MH Baumann, G Tocco, DM Papsun, AL Mohr… - Brain sciences, 2020 - mdpi.com
The recreational use of opioid drugs is a global threat to public health and safety. In
particular, an epidemic of opioid overdose fatalities is being driven by illicitly manufactured …

Sex and gender differences in the effects of novel psychoactive substances

L Fattore, M Marti, R Mostallino, MP Castelli - Brain sciences, 2020 - mdpi.com
Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses
to drugs. Men are more likely than women to use almost all types of illicit drugs and to …

[HTML][HTML] In vitro and in vivo pharmaco-dynamic study of the novel fentanyl derivatives: Acrylfentanyl, Ocfentanyl and Furanylfentanyl

S Bilel, JA Neto, R Arfe, M Tirri, RM Gaudio… - …, 2022 - Elsevier
Fentanyl derivatives (FENS) belongs to the class of Novel Synthetic Opioids that emerged in
the illegal drug market of New Psychoactive Substances (NPS). These substances have …