A brief insight into the etiology, genetics, and immunology of polycystic ovarian syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is a prevailing endocrine and metabolic disorder
occurring in about 6–20% of females in reproductive age. Most symptoms of PCOS arise …
occurring in about 6–20% of females in reproductive age. Most symptoms of PCOS arise …
Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects
B Ducreux, C Patrat, J Trasler… - Human Reproduction …, 2024 - academic.oup.com
Background Millions of children have been born throughout the world thanks to ARTs, the
harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the …
harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the …
Microbiota alters and its correlation with molecular regulation underlying depression in PCOS patients
L Yu, X Chen, X Bai, J Fang, M Sui - Molecular Neurobiology, 2023 - Springer
Depression is one of the complications in patients with polycystic ovary syndrome (PCOS)
that leads to considerable mental health. Accumulating evidence suggests that human gut …
that leads to considerable mental health. Accumulating evidence suggests that human gut …
Transcriptomic screening to identify hub genes and drug signatures for PCOS based on RNA-Seq data in granulosa cells
M Zanjirband, M Baharlooie, Z Safaeinejad… - Computers in Biology …, 2023 - Elsevier
Background Polycystic ovary syndrome (PCOS) is one of the most incident reproductive
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …
diseases, and remains the main cause of female infertility. Granulosa cells play a critical role …
Resveratrol regulates the inflammation and oxidative stress of granulosa cells in PCOS via targeting TLR2
B Yuan, S Luo, L Feng, J Wang, J Mao… - Journal of Bioenergetics …, 2022 - Springer
Polycystic ovary syndrome (PCOS) is featured as a common endocrine disorder in
reproductive-aged women, while its pathophysiology is not fully illustrated. This study …
reproductive-aged women, while its pathophysiology is not fully illustrated. This study …
SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturation
F Yuan, X Hao, Y Cui, FX Huang, X Zhang, Y Sun… - Cell Death & …, 2022 - nature.com
Germ cell division and differentiation require intimate contact and interaction with the
surrounding somatic cells. Luteinizing hormone (LH) triggers epidermal growth factor (EGF) …
surrounding somatic cells. Luteinizing hormone (LH) triggers epidermal growth factor (EGF) …
Updated experimental cellular models to study polycystic ovarian syndrome
G Sudhakaran, SR Babu, H Mahendra, J Arockiaraj - Life Sciences, 2023 - Elsevier
Polycystic ovarian syndrome (PCOS) develops due to hormonal imbalance and
hyperandrogenism. Animal models are widely used to study PCOS because they mimic …
hyperandrogenism. Animal models are widely used to study PCOS because they mimic …
Expression profile analysis of LncRNAs and mRNAs in pre-receptive endometrium of women with polycystic ovary syndrome undergoing in vitro fertilization-embryo …
X Xu, A Yang, P Tian, K Zhang, Y Liu, Y Wang… - BMC Medical …, 2024 - Springer
Background To compare the expression levels of long non-coding RNA (lncRNA) and
messenger RNA (mRNA) in pre-receptive endometrium between patients with Polycystic …
messenger RNA (mRNA) in pre-receptive endometrium between patients with Polycystic …
Metabolome implies increased fatty acid utilization and histone methylation in the follicles from hyperandrogenic PCOS women
Y Xu, Z Zhou, G Zhang, Z Yang, Y Shi, Z Jiang… - The Journal of …, 2024 - Elsevier
Well-balanced metabolism is essential for the high-quality of oocytes, and metabolic
fluctuations of follicular microenvironment potentially encourage functional changes in …
fluctuations of follicular microenvironment potentially encourage functional changes in …
Integrated bioinformatics analysis elucidates granulosa cell whole-transcriptome landscape of PCOS in China
Q Li, Y Sang, Q Chen, B Ye, X Zhou, Y Zhu - Journal of Ovarian Research, 2023 - Springer
Background Polycystic ovary syndrome (PCOS) is a common reproductive, neuroendocrine,
and metabolic disorder in women of reproductive age that affects up to 5–10% of women of …
and metabolic disorder in women of reproductive age that affects up to 5–10% of women of …