Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection

RJ Reiter, R Sharma, F Simko… - Cellular and Molecular …, 2022 - Springer
Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …

[HTML][HTML] The acute and chronic implications of the COVID-19 virus on the cardiovascular system in adults: A systematic review

RE Ashton, BE Philips, M Faghy - Progress in Cardiovascular Diseases, 2023 - Elsevier
Abstract Despite coronavirus disease 2019 (COVID-19) primarily being identified as a
respiratory illness, some patients who seemingly recovered from initial infection, developed …

Antioxidant, anti-inflammatory, and immunomodulatory roles of nonvitamin antioxidants in anti-SARS-CoV-2 therapy

AM Pisoschi, F Iordache, L Stanca… - Journal of Medicinal …, 2022 - ACS Publications
Viral pathologies encompass activation of pro-oxidative pathways and inflammatory burst.
Alleviating overproduction of reactive oxygen species and cytokine storm in COVID-19 is …

The role of SARS-CoV-2-mediated NF-κB activation in COVID-19 patients

Q Zhou, L Zhang, Y Dong, Y Wang, B Zhang… - Hypertension …, 2023 - nature.com
Abstract The SARS-CoV-2 pandemic, now in its third year, has had a profound impact on
public health and economics all over the world. Different populations showed varied …

[HTML][HTML] The need for a multi-level drug targeting strategy to curb the COVID-19 pandemic

GJ Kontoghiorghes, S Fetta… - Frontiers in Bioscience …, 2021 - imrpress.com
Thousands of drugs, nutraceuticals and their combinations can be used to select candidate
therapeutics for targeting SARS-CoV-2 and its symptoms in order to curb COVID-19. A …

The interplay of oxidative stress and immune dysfunction in Hashimoto's thyroiditis and polycystic ovary syndrome: a comprehensive review

G Batóg, A Dołoto, E Bąk, I Piątkowska-Chmiel… - Frontiers in …, 2023 - frontiersin.org
In recent years, there has been a significant increase in the concomitant incidence of
Hashimoto's thyroiditis (HT) and polycystic ovary syndrome (PCOS), both in terms of …

Sunlight exposure and phototherapy: Perspectives for healthy aging in an era of COVID-19

T Nakano, KC Chiang, CC Chen, PJ Chen… - International journal of …, 2021 - mdpi.com
Most humans depend on sunlight exposure to satisfy their requirements for vitamin D3.
However, the destruction of the ozone layer in the past few decades has increased the risk …

Reactive sulfur compounds in the fight against COVID-19

M Iciek, A Bilska-Wilkosz, M Kozdrowicki, M Górny - Antioxidants, 2022 - mdpi.com
The SARS-CoV-2 coronavirus pandemic outbreak in 2019 resulted in the need to search for
an effective and safe strategy for treating infected patients, relieving symptoms, and …

α-Lipoic acid alleviates myocardial injury and induces M2b macrophage polarization after myocardial infarction via HMGB1/NF-kB signaling pathway

Y Wang, Y Zheng, B Qi, Y Liu, X Cheng, J Feng… - International …, 2023 - Elsevier
Background Myocardial infarction (MI) is a serious cardiovascular disease with a poor
prognosis. Macrophages are the predominant immune cells in patients with MI and …

Biopolymeric prodrug systems as potential antineoplastic therapy

AA Chis, AM Arseniu, C Morgovan, CM Dobrea, A Frum… - Pharmaceutics, 2022 - mdpi.com
Nowadays, cancer represents a major public health issue, a substantial economic issue,
and a burden for society. Limited by numerous disadvantages, conventional chemotherapy …