Background The prescription of antidepressant drugs during pregnancy has been steadily
increasing for several decades. Meta-analyses (MAs), which increase the statistical power …

Cardiovascular development is a complex developmental process starting with the formation
of an early straight heart tube, followed by a rightward looping and the configuration of atrial …

Background: Due to the advances in catheter-based interventional techniques, a wide range
of heart diseases can now be treated with a purely interventional approach. Little is yet …

A six-fold increase in congenital heart defects (CHD) exists among monochorionic (MC)
twins compared to singleton or dichorionic twin pregnancies. Though MC twins share an …

Background Using random forest to predict arrhythmia after intervention in children with
atrial septal defect. Methods We constructed a prediction model of complications after …

Right-to-left pulmonary and cardiac shunts (RLS) are important causes of refractory hypoxia
in the critically-ill perioperative patient. Using a point-of-care ultrasound (POCUS) agitated …

Introduction It is known that pulse pressure variation and systolic pressure variation cannot
predict fluid responsiveness in children. In adults, the ability of these dynamic parameters to …

Circulating steroids, including sex hormones, can affect cardiac development and function.
In mammals, steroid sulfatase (STS) is the enzyme solely responsible for cleaving sulfate …

Introduction Right ventricular (RV) fibrosis represents both adaptive and maladaptive
responses to the overloaded RV condition. Its role in pulmonary hypertension (PH) …

Background Despite correction of the atrial septal defect (ASD), patients experience atrial
fibrillation frequently and have increased morbidity and mortality. We examined physical …