Degenerative mitral valve disease (MVD), the most common acquired heart disease in small-
sized dogs, is characterized by valvular degeneration resulting in systolic mitral valve …

Background Dilated cardiomyopathy (DCM) is the most common cardiac disease in large
breed dogs. The disease can start with arrhythmias or with systolic dysfunction of the …

Muscular Dystrophy, convened a Working Group meeting on July 2014, in Bethesda, MD, to
explore clinical and research questions related to cardiac disease in patients with DMD. As …

Objectives: This study sought to evaluate the natural history of occult cardiac dysfunction in
Duchenne muscular dystrophy (DMD). Background: Duchenne muscular dystrophy is …

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease that affects boys and
leads to early death. In the quest for new treatments that improve the quality of life and in the …

Systolic and diastolic dysfunction of the left ventricle (LV) is a hallmark of most cardiac
diseases. In vivo assessment of heart function in animal models, particularly mice, is …

Background: Diagnosis of pulmonary arterial hypertension (PAH) relies on Doppler
measurement of pulmonic and tricuspid regurgitation (TR). However, these are not always …

Dilated cardiomyopathy (DCM) is a frequent cause of cardiac disability, congestive heart
failure (CHF), and arrhythmic death in dogs. The etiology of DCM is usually …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy.
There is no effective treatment and patients typically die in approximately the third decade …

Aims Currently available non-invasive imaging methods frequently fail to detect alterations
in left ventricular (LV) function despite histological evidence of injury. Tissue Doppler …