Numerous analyses of large patient cohorts identified specific patterns of immune activation
associated with patient survival. We established these as the immune contexture …

Substantial evidence shows that inflammation promotes oncogenesis and, occasionally,
participates in cancer rejection. This paradox can be accounted for by a dynamic switch from …

Immune cells infiltrating the microenvironment of melanoma metastases may either limit or
promote tumor progression, but the characteristics that distinguish these effects are obscure …

Innate and adaptive immune system cells play a major role in regulating the growth of
cancer. Although it is commonly thought that an immune response localized to the tumor will …

Purpose: Skin metastases of breast cancer remain a therapeutic challenge. Toll-like receptor
7 agonist imiquimod is an immune response modifier and can induce immune-mediated …

Understanding the biomolecular interactions between graphene and human immune cells is
a prerequisite for its utilization as a diagnostic or therapeutic tool. To characterize the …

Cancer immunotherapy is revolutionizing the clinical management of several tumors, but
has demonstrated limited activity in breast cancer. The development of more effective …

Purpose: Tumor antigen–loaded dendritic cells (DC) are believed to activate antitumor
immunity by stimulating T cells, and CTL-associated antigen 4 (CTLA4)–blocking antibodies …

Palucka K, Ueno H, Fay J, Banchereau J (Baylor Institute for Immunology Research and
Sammons Cancer Center, Baylor University Medical Center, Dallas, TX; and Department of …

Background Although the sequence of events leading to wound repair has been described
at the cellular and, to a limited extent, at the protein level this process has yet to be fully …