Diabetes-related complications are a significant source of morbidity and mortality worldwide.
Diabetic kidney disease is a frequent microvascular complication and a primary cause of …

Almost 200 years ago, the first evidence described by Robert Bright (1836) showed the
strong interaction between the kidneys and heart and, since then, the scientific community …

Intercellular communication governs multicellular interactions in complex organisms. A
variety of mechanisms exist through which cells can communicate, eg, cell-cell contact, the …

Urinary extracellular vesicles (uEV) are a largely unexplored source of kidney-derived
mRNAs with potential to serve as a liquid kidney biopsy. We assessed∼ 200 uEV mRNA …

Exosomes, which are membrane‐bound extracellular vesicles (EVs), are generated in the
endosomal compartment of almost all eukaryotic cells. They are formed upon the fusion of …

Hypertension-mediated organ damage frequently includes renal function decline in which
several mechanisms are involved. The present review outlines the state of the art on …

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease without early
diagnostic and specific therapeutic approaches. Podocyte apoptosis and loss play important …

Comprehensive reviews and large population-based cohort studies have played an
important role in the diagnosis and treatment of pancreatitis and its sequelae. The incidence …

The extracellular vesicles (EVs) released by cells play a crucial role in intercellular
communications and interactions. The direct shedding of EVs from the plasma membrane …

Extracellular vesicles (EVs) are nanoparticles that transmit molecules from releasing cells to
target cells. Recent studies link urinary EVs (uEV) to diverse processes such as infection …