The coronavirus-disease 2019 (COVID-19) was announced as a global pandemic by the
World Health Organization. Challenges arise concerning how to optimally support the …

The preservation of genome integrity in the mammalian female germline from primordial
follicle arrest to activation of growth to oocyte maturation is fundamental to ensure …

Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …

BACKGROUND Mitochondria are multitasking organelles involved in ATP synthesis,
reactive oxygen species (ROS) production, calcium signalling and apoptosis; and …

Apoptosis has been accepted as a fundamental component in the pathogenesis of cancer,
in addition to other human diseases including neurodegeneration, coronary disease and …

Cell-to-cell communication is essential for the development and proper function of
multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) …

Mitochondrial dysfunction is associated with a large number of human diseases, including
neurological and muscular degeneration, cardiovascular disorders, obesity, diabetes, aging …

Background As stem cells of the early embryo mature and differentiate into all tissues, the
mitochondrial complement undergoes dramatic functional improvement. Mitochondrial …

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease that is
characterized by oligo-ovulation or anovulation, hyperandrogenism, and polycystic ovaries …

Mammalian oocytes are long-lived cells in the human body. They initiate meiosis already in
the embryonic ovary, arrest meiotically for long periods in dictyate stage, and resume …