Biochemical and structural basis of sialic acid utilization by gut microbes

A Bell, E Severi, CD Owen, D Latousakis… - Journal of Biological …, 2023 - ASBMB
The human gastrointestinal (GI) tract harbors diverse microbial communities collectively
known as the gut microbiota that exert a profound impact on human health and disease. The …

Functional effects of human milk oligosaccharides (HMOs)

M Dinleyici, J Barbieur, EC Dinleyici, Y Vandenplas - Gut Microbes, 2023 - Taylor & Francis
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …

Carbohydrate flow through agricultural ecosystems: Implications for synthesis and microbial conversion of carbohydrates

KE Low, JP Tingley, L Klassen, ML King, X Xing… - Biotechnology …, 2023 - Elsevier
Carbohydrates are chemically and structurally diverse biomolecules, serving numerous and
varied roles in agricultural ecosystems. Crops and horticulture products are inherent sources …

Exposure to 3′ sialyllactose-poor milk during lactation impairs cognitive capabilities in adulthood

E Pisa, A Martire, V Chiodi, A Traversa, V Caputo… - Nutrients, 2021 - mdpi.com
Breast milk exerts pivotal regulatory functions early in development whereby it contributes to
the maturation of brain and associated cognitive functions. However, the specific …

Comparison of twelve human milk oligosaccharides in mature milk from different areas in China in the Chinese Human Milk Project (CHMP) study

W Zhang, J Vervoort, J Pan, P Gao, H Zhu, X Wang… - Food Chemistry, 2022 - Elsevier
Human milk oligosaccharides (HMOs) act as a vital role in the development of infant's gut
microbiome and immune function. This study aimed to measure 12 oligosaccharides in milk …

Dietary supplementation of 3′-sialyllactose or 6′-sialyllactose elicits minimal influence on cognitive and brain development in growing pigs

RK Golden, LT Sutkus, SM Donovan… - Frontiers in Behavioral …, 2024 - frontiersin.org
Sialylated human milk oligosaccharides (HMO), such as 3′-sialyllactose (3′-SL) and 6′-
sialyllactose (6′-SL), are abundant throughout lactation and at much higher concentrations …

Engineered plants provide a photosynthetic platform for the production of diverse human milk oligosaccharides

CR Barnum, B Paviani, G Couture, C Masarweh… - Nature Food, 2024 - nature.com
Human milk oligosaccharides (HMOs) are a diverse class of carbohydrates which support
the health and development of infants. The vast health benefits of HMOs have made them a …

Dairy products and constituents: a review of their effects on obesity and related metabolic diseases

A Li, X Han, L Liu, G Zhang, P Du, C Zhang… - Critical Reviews in …, 2023 - Taylor & Francis
Obesity has become a global public health problem that seriously affects the quality of life.
As an important part of human diet, dairy products contain a large number of nutrients that …

Characterization of milk oligosaccharide and sialic acid content and their influence on brain sialic acid in a lean mouse model for gestational diabetes

F Liu, AJC Tol, F Kuipers, MH Oosterveer… - Heliyon, 2024 - cell.com
Oligosaccharides and sialic acids (Sia) are bioactive components in milk that contribute to
newborn development and health. Hyperglycemia in pregnancy (HIP) can have adverse …

Evaluation of Prebiotic Glycan Composition in Human Milk and Infant Formula: Profile of Galacto-Oligosaccharides and Absolute Quantification of Major Milk …

H Hou, M Wang, S Yang, X Yang, W Sun… - Journal of Agricultural …, 2024 - ACS Publications
Prebiotic oligosaccharides have attracted immense interest in the infant formula (IF) industry
due to their unique health benefits for infants. There is a need for the reasonable …