Chagas disease (CD) is a vector-borne Neglected Zoonotic Disease (NZD) caused by a
flagellate protozoan, Trypanosoma cruzi, that affects various mammalian species across …

Background Chagas disease (CD) is caused by Trypanosoma cruzi, which is transmitted
mainly through the feces/urine of infected triatomine bugs. The acute phase lasts 2–3 …

In this work, a dual detection system based on an impedimetric immunosensor was
developed for the first time for the simultaneous detection of anti-Trypanosoma cruzi and anti …

Background Chagas disease (CD) is caused by Trypanosoma cruzi. The chronic phase of
CD is characterized by the presence of IgG anti-T. cruzi antibodies; and diagnosis is …

Background Enzyme-linked immunosorbent assays (ELISA) are generally the chosen test
for Chagas disease (CD) diagnosis; however, its performance depends on the antigen …

Diagnosis of Trypanosoma cruzi (T. cruzi) infection in the chronic phase of Chagas disease
(CD) is performed by serologic testing. Conventional tests are currently used with very good …

Extracellular vesicles (EVs) are lipid bilayer envelopes that encase several types of
molecules. Their contents mostly reflect their cell origin and possible targets at other …

Despite several available methodologies for Chagas disease (CD) serological screening,
the main limitation of chronic CD diagnosis is the lack of effective tools for large‐scale …

Chagas disease (CD) is among the top 10 causes of inability to blood donation. Blood
donation centers screen for anti-Trypanosoma cruzi antibodies using highly sensitive …

Background Chagas disease (CD) serological screening at blood banks is usually
performed by a single highly sensitive serological assay, with chemiluminescent …