The endothelium is one of the largest organ systems in the body, and data continue to
emerge regarding the importance of endothelial cell (EC) dysfunction in vascular aging and …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

Low blood flow through the fetal left heart is often conjectured as an etiology for hypoplastic
left heart syndrome (HLHS). To investigate if a decrease in left heart flow results in growth …

Endothelial-to-mesenchymal transition (EndoMT) is the process of endothelial cells
progressively losing endothelial-specific markers and gaining mesenchymal phenotypes. In …

The difficulty and poor prognosis of malignant tumor have always been a difficult problem to
be solved. The internal components of solid tumor are complex, including tumor cells …

Endothelial cells (ECs) line the luminal surface of blood vessels and play a major role in
vascular (patho)-physiology by acting as a barrier, sensing circulating factors and …

Heart failure (HF) is a leading cause of morbidity and mortality particularly in older adults
and patients with multiple metabolic comorbidities. Heart failure with preserved ejection …

High altitude exposure leads to various cognitive impairments. The cerebral vasculature
system plays an integral role in hypoxia‐induced cognitive defects by reducing oxygen and …

Endothelial-to-mesenchymal transition (EndMT) is a physiological process that is equally
important during development and under certain pathological conditions in adult tissues …