Dietary carbohydrates and fats in nonalcoholic fatty liver disease
H Yki-Järvinen, PK Luukkonen, L Hodson… - Nature reviews …, 2021 - nature.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …
[HTML][HTML] Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans
K Pafili, M Roden - Molecular Metabolism, 2021 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) comprises hepatic alterations with
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
increased lipid accumulation (steatosis) without or with inflammation (nonalcoholic …
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis
D Hendriks, JF Brouwers, K Hamer, MH Geurts… - Nature …, 2023 - nature.com
The lack of registered drugs for nonalcoholic fatty liver disease (NAFLD) is partly due to the
paucity of human-relevant models for target discovery and compound screening. Here we …
paucity of human-relevant models for target discovery and compound screening. Here we …
Emerging mechanisms of cardiovascular protection for the omega-3 fatty acid eicosapentaenoic acid
Patients with well-controlled LDL (low-density lipoprotein) levels still have residual
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …
cardiovascular risk associated with elevated triglycerides. Epidemiological studies have …
Treatment of NAFLD with diet, physical activity and exercise
Lifestyle intervention can be effective when treating non-alcoholic fatty liver diseases
(NAFLD) patients. Weight loss decreases cardiovascular and diabetes risk and can also …
(NAFLD) patients. Weight loss decreases cardiovascular and diabetes risk and can also …
Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects
This narrative review aims to discuss the more relevant evidence on the role of linoleic acid
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …
Dietary and policy priorities for cardiovascular disease, diabetes, and obesity: a comprehensive review
D Mozaffarian - Circulation, 2016 - Am Heart Assoc
Suboptimal nutrition is a leading cause of poor health. Nutrition and policy science have
advanced rapidly, creating confusion yet also providing powerful opportunities to reduce the …
advanced rapidly, creating confusion yet also providing powerful opportunities to reduce the …
[HTML][HTML] Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet–a randomised controlled trial
M Holmer, C Lindqvist, S Petersson… - JHEP Reports, 2021 - Elsevier
Background & Aims The first-line treatment for non-alcoholic fatty liver disease (NAFLD) is
weight reduction. Several diets have been proposed, with various effects specifically on liver …
weight reduction. Several diets have been proposed, with various effects specifically on liver …
Overview of non-alcoholic fatty liver disease (NAFLD) and the role of sugary food consumption and other dietary components in its development
P Vancells Lujan, E Vinas Esmel… - Nutrients, 2021 - mdpi.com
NAFLD is the world's most common chronic liver disease, and its increasing prevalence
parallels the global rise in diabetes and obesity. It is characterised by fat accumulation in the …
parallels the global rise in diabetes and obesity. It is characterised by fat accumulation in the …
Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars
OBJECTIVE Nonalcoholic fatty liver disease (ie, increased intrahepatic triglyceride [IHTG]
content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue …
content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue …