Sepsis is the leading cause of death in critically ill patients in intensive care units. Early
recognition of sepsis and proper therapy are essential to reduce patient mortality. Moreover …

Neutrophil extracellular traps (NETs) have recently been discovered as a central part of
antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also …

Drugs that can protect against organ damage are urgently needed, especially for diseases
such as sepsis and brain stroke. We discovered that terazosin (TZ), a widely marketed α1 …

Many cancer cells are known to have defects in the apoptosis machinery. Therefore
identification of compounds that can activate or promote apoptosis in cancer cells is an …

Inhibitors of protein deacetylases represent a novel therapeutic option for cancer diseases
due to their effects on transcriptional regulation by interfering with histones acetylation and …

Dioscin has been shown to promote anticancer activity against several forms of cancers.
However, its detailed molecular mechanisms have not been clarified. In this study, we …

Glioma is a complex disease that is unlikely to result from the effect of a single gene. Genetic
analysis at the pathway level involving multiple genes may be more likely to capture gene …

AIM OF THE STUDY: To evaluate the cytotoxicity and apoptosis induction effects of a novel
lipid-soluble extract (PE) from Pinellia pedatisecta Schott on CaSki, HeLa and HBL-100 …

Multidrug resistance (MDR) is a critical problem in the chemotherapy of cancers. Human
hepatocellular carcinoma (HCC) responds poorly to chemotherapy owing to its potent MDR …

An overview of both experimental and theoretical studies of cell electrophoresis mobility
(EPM) over the past fifty years and the relevance of cell EPM measurement are presented …