Abstract Interleukin-22 (IL-22) is an IL-10 family cytokine produced by T cells and innate
lymphoid cells. The IL-22 signaling pathway orchestrates mucosal immune defense and …

Myelodysplastic syndromes (MDS) are malignant hematopoietic stem cell disorders that
have the capacity to progress to acute myeloid leukemia (AML). Accumulating evidence …

Background Knowledge of immune cell phenotypes, function, and developmental trajectory
in acute myeloid leukemia (AML) microenvironment is essential for understanding …

NLRP3 inflammasome has been reported to be associated with the pathogenesis of multiple
solid tumors. However, the role of NLRP3 inflammasome in acute myeloid leukemia (AML) …

The transformation and progression of myelodysplastic syndromes (MDS) to secondary
acute myeloid leukemia (sAML) involve genetic, epigenetic, and microenvironmental factors …

Abstract T helper 17 (Th17) cells have a prominent role in autoimmune diseases. In contrast,
the nature of these cells in cancer is controversial, with either pro-or antitumorigenic …

Abstract T helper 22 (Th22) cell populations are a newly identified subset of CD4+ T cells
that primarily mediate biological effects on the epithelial barrier through interleukin (IL)‐22 …

B-cell chronic lymphocytic leukemia (B-CLL) is the main cause of mortality among
hematologic diseases in Western nations. B-CLL is correlated with an intense alteration of …

Non-Hodgkin's lymphomas (NHLs) are a heterogeneous group of neoplasm in which 90%
are B-cell lymphomas and 10% T-cell lymphomas. Although T-helper 17 (Th17) cells have …

Acute myeloid leukemia (AML) is a hematological malignancy in which the immune
response serves a pivotal role in progression. Aryl hydrocarbon receptor (AHR) is involved …