Recent studies demonstrating epigenetic and developmental sensitivity to early
environments, as exemplified by fields like the Developmental Origins of Health and …

Abstract Purpose of Review Early life presents a pivotal period during which nutritional
exposures are more likely to cause epigenetic modifications, which may impact an …

Importance Preeclampsia, gestational hypertension, and gestational diabetes, the most
common pregnancy complications, are associated with substantial morbidity and mortality in …

Cellular senescence (CS) is defined as a state of terminal proliferation arrest accompanied
by morphological alterations, pro-inflammatory phenotype, and metabolic changes. In recent …

Worldwide increase in life expectancy has boosted research on aging. Overcoming the
concept of chronological age, higher attention has been addressed to biological age, which …

Maternal diabetes and/or obesity in pregnancy are undoubtedly associated with later
disease-risk in the offspring. The placenta, interposed between the mother and the foetus, is …

The incidence of obesity is rising rapidly worldwide with the consequence that more women
are entering pregnancy overweight or obese. This leads to an increased incidence of clinical …

DNA methylation is the most commonly studied epigenetic mark in humans, as it is well
recognised as a stable, heritable mark that can affect genome function and influence gene …

The racial disparity associated with preterm birth is a public health concern in the United
States. The placenta is the principal metabolic, respiratory, and endocrine organ of the fetus …

Human social epigenomics research is critical to elucidate the intersection of social and
genetic influences underlying racial and ethnic differences in health and development …