Non-viral vectors for RNA delivery
Y Yan, XY Liu, A Lu, XY Wang, LX Jiang… - Journal of Controlled …, 2022 - Elsevier
RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …
Non-invasive delivery strategies for biologics
AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
[HTML][HTML] Cell penetrating peptides: A concise review with emphasis on biomedical applications
H Derakhshankhah, S Jafari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …
survival and function of living cells. However, these natural barriers could be a major …
Immunomodulatory nanosystems
Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …
[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …
because many diseases affect the retina and choroid leading to impaired vision or …
Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
Ocular drug delivery: present innovations and future challenges
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
Small bioactive peptides for biomaterials design and therapeutics
IW Hamley - Chemical reviews, 2017 - ACS Publications
This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …
sequences for a range of applications ranging from biomaterials development to peptides …
Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …
Cell-penetrating peptides: design, synthesis, and applications
DM Copolovici, K Langel, E Eriste, U Langel - ACS nano, 2014 - ACS Publications
The intrinsic property of cell-penetrating peptides (CPPs) to deliver therapeutic molecules
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …
(nucleic acids, drugs, imaging agents) to cells and tissues in a nontoxic manner has …