Comparative analysis of CNV calling algorithms: literature survey and a case study using bovine high-density SNP data
Copy number variations (CNVs) are gains and losses of genomic sequence between two
individuals of a species when compared to a reference genome. The data from single …
individuals of a species when compared to a reference genome. The data from single …
Innovative trial design in precision oncology
Genomic profiling technologies have enabled the development of targeted therapies
designed to target specific biomarkers and molecular pathways involved in the …
designed to target specific biomarkers and molecular pathways involved in the …
A two-sample test for equality of means in high dimension
KB Gregory, RJ Carroll… - Journal of the …, 2015 - Taylor & Francis
We develop a test statistic for testing the equality of two population mean vectors in the
“large-p-small-n” setting. Such a test must surmount the rank-deficiency of the sample …
“large-p-small-n” setting. Such a test must surmount the rank-deficiency of the sample …
Assessing systematic effects of stroke on motor control by using hierarchical function-on-scalar regression
J Goldsmith, T Kitago - Journal of the Royal Statistical Society …, 2016 - academic.oup.com
This work is concerned with understanding common population level effects of stroke on
motor control while accounting for possible subject level idiosyncratic effects. Upper …
motor control while accounting for possible subject level idiosyncratic effects. Upper …
Reproducibility of differential proteomic technologies in CPTAC fractionated xenografts
The NCI Clinical Proteomic Tumor Analysis Consortium (CPTAC) employed a pair of
reference xenograft proteomes for initial platform validation and ongoing quality control of its …
reference xenograft proteomes for initial platform validation and ongoing quality control of its …
Subgroup-based adaptive (SUBA) designs for multi-arm biomarker trials
Targeted therapies based on biomarker profiling are becoming a mainstream direction of
cancer research and treatment. Depending on the expression of specific prognostic …
cancer research and treatment. Depending on the expression of specific prognostic …
Bayesian hierarchical structured variable selection methods with application to molecular inversion probe studies in breast cancer
L Zhang, V Baladandayuthapani… - Journal of the Royal …, 2014 - academic.oup.com
The analysis of genomics alterations that may occur in nature when segments of
chromosomes are copied (known as copy number alterations) has been a focus of research …
chromosomes are copied (known as copy number alterations) has been a focus of research …
Bayesian inference and dynamic prediction for multivariate longitudinal and survival data
The supplementary material consists of:(1). the estimation of the covariance matrices;(2). the
expression and justification of the Gaussian Quadrature approximation;(3). the model fitting …
expression and justification of the Gaussian Quadrature approximation;(3). the model fitting …
Statistical contributions to bioinformatics: design, modelling, structure learning and integration
JS Morris, V Baladandayuthapani - Statistical modelling, 2017 - journals.sagepub.com
The advent of high-throughput multi-platform genomics technologies providing whole-
genome molecular summaries of biological samples has revolutionalized biomedical …
genome molecular summaries of biological samples has revolutionalized biomedical …
Generalized species sampling priors with latent beta reinforcements
EM Airoldi, T Costa, F Bassetti, F Leisen… - Journal of the …, 2014 - Taylor & Francis
Many popular Bayesian nonparametric priors can be characterized in terms of
exchangeable species sampling sequences. However, in some applications …
exchangeable species sampling sequences. However, in some applications …