The authors were asked by the Editors of ACS Chemical Biology to write an article titled
“Why Nature Chose Selenium” for the occasion of the upcoming bicentennial of the …

Cancer cells produce high amounts of reactive oxygen species (ROS) and evade apoptosis.
Hydroperoxides support proliferation, invasion, migration and angiogenesis, but at higher …

Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Background: Determination of the presence or absence of bacterial infection is important to
guide appropriate therapy and reduce antibiotic exposure. Procalcitonin (PCT) is an …

Deregulation of transcription is a hallmark of acute myeloid leukemia (AML) that drives
oncogenic expression programs and presents opportunities for therapeutic targeting. By …

Of the many health benefits attributed to selenium, the one that has received the most
attention is its role in cancer prevention. Selenium-containing proteins (selenoproteins) have …

Viewpoints informative in designing clinical studies for elucidating specific roles of selenium
in human biology. Then, supplementation with selenium could be targeted to a subset of the …

The micronutrient element selenium (Se) has been shown to be effective in reducing the
incidence of cancer in animal models and human clinical trials. Selenoproteins and low …

The latest developments of epidemiologic and biochemical research suggest that current
upper limits of intake for dietary selenium and for overall selenium exposure may be …

The biological activity of amorphous selenium nanoparticles (SeNPs) was limited by their
poor stability and rapid spontaneous phase transformation. Herein, we prepared amorphous …