Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections

Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …

Antimicrobial peptides: Structure, mechanism, and modification

N Chen, C Jiang - European Journal of Medicinal Chemistry, 2023 - Elsevier
From the 1940s to the 1960s, the discovery of antibiotics held substantial promise for the
treatment of bacterial infection, and it was also widely used in food, agriculture, and other …

[HTML][HTML] Focus: antimicrobial resistance: antimicrobial peptides therapy: an emerging alternative for treating drug-resistant bacteria

IE Mba, EI Nweze - The Yale journal of biology and medicine, 2022 - ncbi.nlm.nih.gov
Microbial resistance to antibiotics is an ancient and dynamic issue that has brought a
situation reminiscent of the pre-antibiotic era to the limelight. Currently, antibiotic resistance …

Unraveling the role of antimicrobial peptides in insects

S Stączek, M Cytryńska… - International Journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are short, mainly positively charged, amphipathic molecules.
AMPs are important effectors of the immune response in insects with a broad spectrum of …

Mechanisms and regulation of defensins in host defense

J Fu, X Zong, M Jin, J Min, F Wang… - Signal Transduction and …, 2023 - nature.com
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Bromelain and nisin: The natural antimicrobials with high potential in biomedicine

U Jančič, S Gorgieva - Pharmaceutics, 2021 - mdpi.com
Infectious diseases along with various cancer types are among the most significant public
health problems and the leading cause of death worldwide. The situation has become even …

[HTML][HTML] Antimicrobial plant-derived peptides obtained by enzymatic hydrolysis and fermentation as components to improve current food systems

F Rivero-Pino, MJ Leon, MC Millan-Linares… - Trends in Food Science …, 2023 - Elsevier
Background New challenges in our society are appearing following the emergence of
antibiotic-resistant microorganisms and the concerns about the use of antibiotics …

An overview of the potentialities of antimicrobial peptides derived from natural sources

I Dini, MG De Biasi, A Mancusi - Antibiotics, 2022 - mdpi.com
Antimicrobial peptides (AMPs) are constituents of the innate immune system in every kind of
living organism. They can act by disrupting the microbial membrane or without affecting …

Recent advances in the development and application of peptide self-assemblies in infection control

T Ge, X Hu, M Liao, F Zhou, JR Lu - Current Opinion in Colloid & Interface …, 2023 - Elsevier
Peptide self-assemblies display distinct physical and structural transitions, featured from the
early small assemblies or oligomers, long nanosheets, nanobelts, nanotubes and …