[HTML][HTML] Therapeutic strategy of mesenchymal-stem-cell-derived extracellular vesicles as regenerative medicine

Y Matsuzaka, R Yashiro - International Journal of Molecular Sciences, 2022 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

[HTML][HTML] Extracellular vesicles as potential biomarkers in amyotrophic lateral sclerosis

M Barbo, M Ravnik-Glavač - Genes, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is described as a fatal and rapidly progressive
neurodegenerative disorder caused by the degeneration of upper motor neurons in the …

[HTML][HTML] Chronic nSMase inhibition suppresses neuronal exosome spreading and sex-specifically attenuates amyloid pathology in APP knock-in Alzheimer's disease …

FE Mowry, F Espejo-Porras, S Jin, Z Quadri, L Wu… - Neurobiology of …, 2023 - Elsevier
Female biased pathology and cognitive decline in Alzheimer's disease (AD) have been
consistently observed with unclear underlying mechanisms. Although brain sphingolipid …

[HTML][HTML] Long non-coding RNAs, extracellular vesicles and inflammation in Alzheimer's disease

A Canseco-Rodriguez, V Masola, V Aliperti… - International Journal of …, 2022 - mdpi.com
Alzheimer's Disease (AD) has currently no effective treatment; however, preventive
measures have the potential to reduce AD risk. Thus, accurate and early prediction of risk is …

Most recent advances and applications of extracellular vesicles in tackling neurological challenges

M Kaur, S Fusco, B Van den Broek… - Medicinal Research …, 2024 - Wiley Online Library
Over the past few decades, there has been a notable increase in the global burden of
central nervous system (CNS) diseases. Despite advances in technology and therapeutic …

[HTML][HTML] Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine …

S Jin, X Chen, Y Tian, R Jarvis, V Promes… - Nature …, 2023 - nature.com
Developing astroglia play important roles in regulating synaptogenesis through secreted
and contact signals. Whether they regulate postnatal axon growth is unknown. By selectively …

[HTML][HTML] Molecular hallmarks of ageing in amyotrophic lateral sclerosis

CJ Jagaraj, S Shadfar, SA Kashani… - Cellular and Molecular …, 2024 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal, severely debilitating and rapidly progressing
disorder affecting motor neurons in the brain, brainstem, and spinal cord. Unfortunately …

Urinary biomarkers for amyotrophic lateral sclerosis: candidates, opportunities and considerations

ML Rogers, DW Schultz, V Karnaros… - Brain …, 2023 - academic.oup.com
Amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal
within 3–5 years and is diagnosed on evidence of progressive upper and lower motor …

Genetically engineered neural stem cells (NSCs) therapy for neurological diseases; state‐of‐the‐art

G Lutfi Ismaeel, OJ Makki AlHassani… - Biotechnology …, 2023 - Wiley Online Library
Neural stem cells (NSCs) are multipotent stem cells with remarkable self‐renewal potential
and also unique competencies to differentiate into neurons, astrocytes, and …

[图书][B] Advances in clinical chemistry

H Sobotka, CP Stewart - 1964 - books.google.com
Volume 7 of Advances in Clinical Chemistry ranges over the whole gamut of the subject. The
broad scope presented here is a deliberate act of policy-the aim is to emphasize the …