Low-level antimicrobials in the medicinal leech select for resistant pathogens that spread to patients

L Beka, MS Fullmer, SM Colston, MC Nelson… - MBio, 2018 - Am Soc Microbiol
ABSTRACT Fluoroquinolones (FQs) and ciprofloxacin (Cp) are important antimicrobials that
pollute the environment in trace amounts. Although Cp has been recommended as …

Host matters: medicinal leech digestive-tract symbionts and their pathogenic potential

JN Marden, EA McClure, L Beka, J Graf - Frontiers in Microbiology, 2016 - frontiersin.org
Digestive-tract microbiota exert tremendous influence over host health. Host-symbiont model
systems are studied to investigate how symbioses are initiated and maintained, as well as to …

Marine leech anticoagulant diversity and evolution

M Tessler, D Marancik… - The Journal of …, 2018 - meridian.allenpress.com
Abstract Leeches (Annelida: Hirudinea) possess powerful salivary anticoagulants and,
accordingly, are frequently employed in modern, authoritative medicine. Members of the …

The Animal Model Determines the Results of Aeromonas Virulence Factors

A Romero, PR Saraceni, S Merino, A Figueras… - Frontiers in …, 2016 - frontiersin.org
The selection of an experimental animal model is of great importance in the study of
bacterial virulence factors. Here, a bath infection of zebrafish larvae is proposed as an …

Neuro-immune lessons from an annelid: the medicinal leech

A Tasiemski, M Salzet - Developmental & Comparative Immunology, 2017 - Elsevier
An important question that remains unanswered is how the vertebrate neuroimmune system
can be both friend and foe to the damaged nervous tissue. Some of the difficulty in obtaining …

First Isolation of a Giant Virus from Wild Hirudo medicinalis Leech: Mimiviridae isolation in Hirudo medicinalis

M Boughalmi, I Pagnier, S Aherfi, P Colson, D Raoult… - Viruses, 2013 - mdpi.com
Giant viruses and amoebae are common in freshwater, where they can coexist with other
living multicellular organisms. We screened leeches from the species Hirudo medicinalis for …

Characterization of the digestive tract microbiota of Hirudo orientalis (medicinal leech) and antibiotic resistance profile

IS Whitaker, M Maltz, ME Siddall… - Plastic and reconstructive …, 2014 - journals.lww.com
Background: There are at least three distinct European leech species used medicinally:
Hirudo medicinalis, H. orientalis, and H. verbana. Infection caused by leech microbiota is the …

Metagenomic analysis of the medicinal leech gut microbiota

MA Maltz, L Bomar, P Lapierre, HG Morrison… - Frontiers in …, 2014 - frontiersin.org
There are trillions of microbes found throughout the human body and they exceed the
number of eukaryotic cells by 10-fold. Metagenomic studies have revealed that the majority …

The energy metabolism of the freshwater leech Whitmania pigra in response to fasting

J Liu, P Jin, M Li, X Yi, Y Tian, Z Zhang, J Liu… - … and Physiology Part B …, 2024 - Elsevier
Non-blood-feeding leeches, Whitmania pigra, have evolved unique digestive structures and
physiological mechanisms to cope with fasting. However, the metabolic changes and …

Ideating iDNA: Lessons and limitations from leeches in legacy collections

ME Siddall, M Barkdull, M Tessler, MR Brugler… - PLoS …, 2019 - journals.plos.org
Indirect methods for conducting faunal inventories present great promise, and genomic
inventories derived from environmental sources (eDNA) are improving. Invertebrate …