Non-union bone fractures

B Wildemann, A Ignatius, F Leung… - Nature reviews Disease …, 2021 - nature.com
The human skeleton has remarkable regenerative properties, being one of the few
structures in the body that can heal by recreating its normal cellular composition, orientation …

Calcium phosphate-based biomaterials for bone repair

X Hou, L Zhang, Z Zhou, X Luo, T Wang… - Journal of functional …, 2022 - mdpi.com
Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Multimaterial 3D and 4D bioprinting of heterogenous constructs for tissue engineering

A Chen, W Wang, Z Mao, Y He, S Chen… - Advanced …, 2024 - Wiley Online Library
Additive manufacturing (AM), which is based on the principle of layer‐by‐layer shaping and
stacking of discrete materials, has shown significant benefits in the fabrication of …

Chitosan-based scaffold for mineralized tissues regeneration

T Sukpaita, S Chirachanchai, A Pimkhaokham… - Marine Drugs, 2021 - mdpi.com
Conventional bone grafting procedures used to treat bone defects have several limitations.
An important aspect of bone tissue engineering is developing novel bone substitute …

Bioactive scaffold (sodium alginate)-g-(nHAp@ SiO2@ GO) for bone tissue engineering

MUA Khan, SI Abd Razak, S Rehman, A Hasan… - International journal of …, 2022 - Elsevier
Globally, people suffering from bone disorders are steadily increasing and bone tissue
engineering is an advanced approach to treating fractured and defected bone tissues. In this …

Nanomaterials supported by polymers for tissue engineering applications: A review

F Habibzadeh, SM Sadraei, R Mansoori… - Heliyon, 2022 - cell.com
In the biomedical sciences, particularly in wound healing, tissue engineering, and
regenerative medicine, the development of natural-based biomaterials as a carrier has …

In vitro static and dynamic cell culture study of novel bone scaffolds based on 3D-printed PLA and cell-laden alginate hydrogel

R Noroozi, MA Shamekhi, R Mahmoudi… - Biomedical …, 2022 - iopscience.iop.org
The aim of this paper was to design and fabricate a novel composite scaffold based on the
combination of 3D-printed polylactic acid-based triply periodic minimal surfaces (TPMSs) …

Hydrogels and bioprinting in bone tissue engineering: creating artificial stem‐cell niches for in vitro models

FK Lewns, O Tsigkou, LR Cox, RD Wildman… - Advanced …, 2023 - Wiley Online Library
Advances in bioprinting have enabled the fabrication of complex tissue constructs with high
speed and resolution. However, there remains significant structural and biological …

Three-dimensional cell cultures: the bridge between in vitro and in vivo models

O Urzì, R Gasparro, E Costanzo, A De Luca… - International Journal of …, 2023 - mdpi.com
Although historically, the traditional bidimensional in vitro cell system has been widely used
in research, providing much fundamental information regarding cellular functions and …

Role and architectural significance of porous chitosan-based scaffolds in bone tissue engineering

S Lekhavadhani, A Shanmugavadivu… - International Journal of …, 2023 - Elsevier
In designing and fabricating scaffolds to fill the bone defects and stimulate new bone
formation, the biomimetics of the construct is a crucial factor in invoking the bone …