Non-coding RNA mediated regulation of PI3K/Akt pathway in hepatocellular carcinoma: Therapeutic perspectives

MS Hussain, E Moglad, M Afzal, G Gupta… - … -Research and Practice, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is among the primary reasons for fatalities caused by
cancer globally, highlighting the need for comprehensive knowledge of its molecular …

Pyroptosis-related non-coding RNAs emerging players in atherosclerosis pathology

WMA Khojali, NE Khalifa, F Alshammari, S Afsar… - … -Research and Practice, 2024 - Elsevier
Globally, atherosclerosis a persistent inflammatory condition of the artery walls continues to
be the primary cause of cardiovascular illness and death. The ncRNAs are important …

Pharmacological bioactivity of Ceratonia siliqua pulp extract: in vitro screening and molecular docking analysis, implication of Keap-1/Nrf2/NF-ĸB pathway

M El-Zeftawy, D Ghareeb - Scientific Reports, 2023 - nature.com
Inflammation is interfaced with various metabolic disorders. Ceratonia siliqua (CS) has a
higher pharmaceutical purpose. The research aimed to investigate the biofunction of CS …

Overcoming chemoresistance and radio resistance in prostate cancer: The emergent role of non-coding RNAs

M Sarfraz, A Khan, L Eltaib, SMB Asdaq… - … -Research and Practice, 2024 - Elsevier
Prostate cancer (PCa) continues to be a major health concern worldwide, with its resistance
to chemotherapy and radiation therapy presenting major hurdles in successful treatment …

Unravelling the role of long non-coding RNAs in modulating the Hedgehog pathway in cancer

SS Chandel, A Mishra, G Dubey, RP Singh… - … -Research and Practice, 2024 - Elsevier
Cancer is a multifactorial pathological condition characterized by uncontrolled cellular
proliferation, genomic instability, and evasion of regulatory mechanisms. It arises from the …

From diagnosis to therapy: The transformative role of lncRNAs in eye cancer management

A Hazazi, AA AlShehah, FR Khan, MA Hakami… - … -Research and Practice, 2024 - Elsevier
The genomic era has brought about a transformative shift in our comprehension of cancer,
unveiling the intricate molecular landscape underlying disease development. Eye cancers …

Evolving Strategies for Use of Phytochemicals in Prevention and Long-Term Management of Cardiovascular Diseases (CVD)

DD Haines, FM Cowan, A Tosaki - International Journal of Molecular …, 2024 - mdpi.com
This report describes major pathomechanisms of disease in which the dysregulation of host
inflammatory processes is a major factor, with cardiovascular disease (CVD) as a primary …

Targeting the Wnt/β-Catenin Cascade in Osteosarcoma: The Potential of ncRNAs as Biomarkers and Therapeutics

S Fuloria, G Yadav, SV Menon, H Ali, K Pant… - … -Research and Practice, 2024 - Elsevier
Osteosarcoma (OS) is a bone cancer which stems from several sources and presents with
diverse clinical features, making evaluation and treatment difficult. Chemotherapy tolerance …

From Oncogenes to Tumor Suppressors: The Dual Role of ncRNAs in Fibrosarcoma

I Kazmi, M Afzal, WH Almalki, SI Alzarea… - … -Research and Practice, 2024 - Elsevier
Fibrosarcoma is a challenging cancer originating from fibrous tissues, marked by aggressive
growth and limited treatment options. The discovery of non-coding RNAs (ncRNAs) …

Examination of Primary and Secondary Metabolites Associated with a Plant-Based Diet and Their Impact on Human Health

M Simsek, K Whitney - Foods, 2024 - mdpi.com
The consumption of plant-based diets has become a burgeoning trend, and they are
increasingly consumed globally owing to their substantial energy intensity and dietetic …