Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

L Zhang, Y Liu, H Huang, H Xie, B Zhang, W Xia… - Advanced drug delivery …, 2022 - Elsevier
Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

Therapeutic efficacy of nanoparticles and routes of administration

D Chenthamara, S Subramaniam… - Biomaterials …, 2019 - spj.science.org
In modern-day medicine, nanotechnology and nanoparticles are some of the indispensable
tools in disease monitoring and therapy. The term “nanomaterials” describes materials with …

Nanomedicine for brain cancer

S Quader, K Kataoka, H Cabral - Advanced Drug Delivery Reviews, 2022 - Elsevier
CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

[HTML][HTML] Progress and perspectives on targeting nanoparticles for brain drug delivery

H Gao - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Overview of current drug delivery methods across the blood–brain barrier for the treatment of primary brain tumors

R Haumann, JC Videira, GJL Kaspers… - CNS drugs, 2020 - Springer
Existing drug delivery methods have not led to a significant increase in survival for patients
with malignant primary brain tumors. While the combination of conventional therapies …

Macrophage-mimic shape changeable nanomedicine retained in tumor for multimodal therapy of breast cancer

R Liu, Y An, W Jia, Y Wang, Y Wu, Y Zhen, J Cao… - Journal of Controlled …, 2020 - Elsevier
The current nanomedicines for cancer therapy based on the enhance permeability and
retention (EPR) effect remain insufficient to satisfy the clinical need, and the challenges …

[HTML][HTML] Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review

E Bellotti, AL Schilling, SR Little, P Decuzzi - Journal of controlled release, 2021 - Elsevier
The central nervous system (CNS), consisting of the brain, spinal cord, and retina,
superintends to the acquisition, integration and processing of peripheral information to …

Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles

A Rodzinski, R Guduru, P Liang, A Hadjikhani… - Scientific reports, 2016 - nature.com
It is a challenge to eradicate tumor cells while sparing normal cells. We used
magnetoelectric nanoparticles (MENs) to control drug delivery and release. The physics is …

Recent trends in the development of hydrogel therapeutics for the treatment of central nervous system disorders

Q Li, X Shao, X Dai, Q Guo, B Yuan, Y Liu… - NPG Asia …, 2022 - nature.com
The central nervous system (CNS) controls the acquisition and processing of peripheral
information to manage the behaviors of organisms. CNS disorders, including CNS injuries …