Cellular hypoxia is the common final pathway of brain injury that occurs not just after
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …

Plants are aerobic organisms that require oxygen for their respiration. Hypoxia arises due to
the insufficient availability of oxygen, and is sensed by plants, which adapt their growth and …

Background The level of environmental hypobaric hypoxia that affects climbers at the
summit of Mount Everest (8848 m [29,029 ft]) is close to the limit of tolerance by humans. We …

Much hypoxia research has been carried out at high altitude in a hypobaric hypoxia (HH)
environment. Many research teams seek to replicate high-altitude conditions at lower …

Objective: The management of hypoxemia in critically ill patients is challenging. Whilst the
harms of tissue hypoxia are well recognized, the possibility of harm from excess oxygen …

Anecdotal evidence surrounding Tibetans' and Sherpas' exceptional tolerance to hypobaric
hypoxia has been recorded since the beginning of high-altitude exploration. These …

Ascent to high altitude is associated with a fall in the partial pressure of inspired oxygen
(hypobaric hypoxia). For oxidative tissues such as skeletal muscle, resultant cellular hypoxia …

Ascent to high altitude is associated with physiological responses that counter the stress of
hypobaric hypoxia by increasing oxygen delivery and by altering tissue oxygen utilisation …

The gut microbiota is involved in host responses to high altitude. However, the dynamics of
intestinal microecology and their association with altitude-related illness are poorly …

Immune outcomes are key mediators of many health benefits of exercise and are
determined by exercise type, dose (frequency/duration, intensity), and individual …