Angiotensin-converting enzyme (ACE) is a zinc-dependent peptidase responsible for
converting angiotensin I into the vasoconstrictor angiotensin II. However, ACE is a relatively …

Background The renin‐angiotensin system (RAS) is a homeostatic pathway widely known to
regulate cardiovascular and renal physiology; however, little is known about its influence in …

The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental
roles in cancer biology which influences cell growth, migration, death, and metastasis. RAAS …

Tonic smooth muscles play pivotal roles in the pathophysiology of debilitating diseases of
the gastrointestinal and cardiovascular systems. Tonic smooth muscles differ from phasic …

The renin-angiotensin system (RAS) is well known for its vital involvement in body fluid
homeostasis and circulation. However, very little research has been devoted to the impact of …

Dietary fats and sodium are both palatable and are hypothesized to synergistically
contribute to ingestive behavior and thereby obesity. Contrary to this hypothesis, C57BL/6J …

Major molecular pathways affecting gastrointestinal (GI) smooth muscle contractility include
Ca2/calmodulin/myosin light chain kinase (MLCK), the protein kinase C (PKC)/CPI-17, and …

Studies have demonstrated that angiotensin II (Ang II) can regulate intestinal fluid and
electrolyte transport and control intestinal wall muscular activity. Ang II is also a …

Background The motility of the upper gut after Roux-en-Y gastric bypass (RYGBP) is
underexplored. We aimed to investigate the oesophago-gastro-Roux limb motor activity …

Aim: Angiotensin II is well known for its contractile effects on smooth muscle cells. This effect
is also present in the gut previously shown in animal models. The aim of this study was to …