Synthesis and biophysical investigations of oligonucleotides containing galactose-modified DNA, LNA, and 2′-amino-LNA monomers
Galactose-modified thymidine, LNA-T, and 2′-amino-LNA-T nucleosides were synthesized,
converted into the corresponding phosphoramidite derivatives and introduced into short …
converted into the corresponding phosphoramidite derivatives and introduced into short …
Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-l-LNA
G-rich anti-parallel DNA triplexes were modified with LNA or α-L-LNA in their Watson–Crick
and TFO strands. The triplexes were formed by targeting a pyrimidine strand to a putative …
and TFO strands. The triplexes were formed by targeting a pyrimidine strand to a putative …
Anti-parallel triplexes: Synthesis of 8-aza-7-deazaadenine nucleosides with a 3-aminopropynyl side-chain and its corresponding LNA analog
The phosphoramidites of DNA monomers of 7-(3-aminopropyn-1-yl)-8-aza-7-deazaadenine
(Y) and 7-(3-aminopropyn-1-yl)-8-aza-7-deazaadenine LNA (Z) are synthesized, and the …
(Y) and 7-(3-aminopropyn-1-yl)-8-aza-7-deazaadenine LNA (Z) are synthesized, and the …
Synthesis of a fluorescence resonance energy transfer-based probe containing a tricyclic nucleoside analog for single nucleotide polymorphism typing
A Hayai, Y Maeda, Y Ueno - Bioorganic & Medicinal Chemistry Letters, 2016 - Elsevier
Here, we report the synthesis of a fluorescence resonance energy transfer (FRET)-based
probe for single nucleotide polymorphism (SNP) typing. The probe contains a fluorescent …
probe for single nucleotide polymorphism (SNP) typing. The probe contains a fluorescent …
Single stranded dna enzyme inhibitors
US20240140983A1 - Single stranded dna enzyme inhibitors - Google Patents
US20240140983A1 - Single stranded dna enzyme inhibitors - Google Patents Single …
US20240140983A1 - Single stranded dna enzyme inhibitors - Google Patents Single …
Nucleotides and nucleic acids; oligo-and poly-nucleotides
D Loakes - 2014 - books.rsc.org
The synthesis of modified oligonucleotides is, as in previous years, divided into sections
describing updates on synthesis, followed by modifications to the backbone, sugar and …
describing updates on synthesis, followed by modifications to the backbone, sugar and …