Treatment of glioblastoma xenografts with chloroquine results in macroautophagy/
autophagy inhibition, resulting in a reduction of tumor hypoxia and sensitization to radiation …

The use of breath-hold techniques in radiotherapy, such as deep-inspiration breath hold, is
increasing although guidelines for clinical implementation are lacking. In these …

Technology has a pivotal role in the continuous development of radiotherapy. The long road
toward modern 'high‐tech'radiation oncology has been studded with discoveries and …

Background Hybrid magnetic resonance (MR)-Linac systems have recently been introduced
into clinical practice. The systems allow online adaption of the treatment plan with the aim of …

Radiation-induced lung injury (RILI) is a form of radiation damage to normal lung tissue
caused by radiotherapy (RT) for thoracic cancers, which is most commonly comprised of …

Background Online adaptive radiation therapy (RT) using hybrid magnetic resonance linear
accelerators (MR‐Linacs) can administer a tailored radiation dose at each treatment fraction …

MR guided radiotherapy represents one of the most promising recent technological
innovations in the field. The possibility to better visualize therapy volumes, coupled with the …

The complex and varied motion of the cervix–uterus target during external beam
radiotherapy (EBRT) underscores the clinical benefits afforded by adaptive radiotherapy …

Image-guided radiotherapy (IGRT) enables optimal tumor targeting and sparing of organs-at-
risk, which ultimately results in improved outcomes for patients. Magnetic resonance …

Background and purpose Daily online adaptation of the clinical target volume (CTV) using
MR-guided radiotherapy enables margin reduction of the planning target volume (PTV). This …