miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

Breast milk, a source of beneficial microbes and associated benefits for infant health

KE Lyons, CA Ryan, EM Dempsey, RP Ross, C Stanton - Nutrients, 2020 - mdpi.com
Human breast milk is considered the optimum feeding regime for newborn infants due to its
ability to provide complete nutrition and many bioactive health factors. Breast feeding is …

Overview of microRNA biogenesis, mechanisms of actions, and circulation

J O'Brien, H Hayder, Y Zayed, C Peng - Frontiers in endocrinology, 2018 - frontiersin.org
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …

MXene-based aptasensors: Advances, challenges, and prospects

S Ullah, F Shahzad, B Qiu, X Fang, A Ammar… - Progress in Materials …, 2022 - Elsevier
The combination of 2D MXenes with high affinity aptamers has resulted in the development
of innovative aptasensing approaches for food/water safety and clinical diagnosis. Aptamers …

Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: a comprehensive review

A Ismail, HA El-Mahdy, AI Abulsoud… - International Journal of …, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

Clinical epigenetics: seizing opportunities for translation

M Berdasco, M Esteller - Nature Reviews Genetics, 2019 - nature.com
Biomarker discovery and validation are necessary for improving the prediction of clinical
outcomes and patient monitoring. Despite considerable interest in biomarker discovery and …

[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Nanozyme-based electrochemical biosensors for disease biomarker detection

RG Mahmudunnabi, FZ Farhana, N Kashaninejad… - Analyst, 2020 - pubs.rsc.org
In recent years, a new group of nanomaterials named nanozymes that exhibit enzyme-
mimicking catalytic activity has emerged as a promising alternative to natural enzymes …

dbDEMC 3.0: functional exploration of differentially expressed miRNAs in cancers of human and model organisms

F Xu, Y Wang, Y Ling, C Zhou, H Wang… - Genomics …, 2022 - academic.oup.com
M icroRNAs (miRNAs) are important regulators in gene expression. The dysregulation of
miRNA expression is widely reported in the transformation from physiological to pathological …

MicroRNAs in neuroinflammation: implications in disease pathogenesis, biomarker discovery and therapeutic applications

JA Slota, SA Booth - Non-coding RNA, 2019 - mdpi.com
The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …