Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors

G Pellegriti, F Frasca, C Regalbuto… - Journal of cancer …, 2013 - Wiley Online Library
Background. In the last decades, thyroid cancer incidence has continuously and sharply
increased all over the world. This review analyzes the possible reasons of this increase …

Diabetes and cancer

P Vigneri, F Frasca, L Sciacca… - Endocrine-related …, 2009 - erc.bioscientifica.com
Diabetes and cancer are two heterogeneous, multifactorial, severe, and chronic diseases.
Because of their frequency, reciprocal influences–even minor influences–may have a major …

Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules

MN Nikiforova, S Mercurio, AI Wald… - Cancer, 2018 - Wiley Online Library
BACKGROUND Molecular tests have clinical utility for thyroid nodules with indeterminate
fine‐needle aspiration (FNA) cytology, although their performance requires further …

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease

A Belfiore, F Frasca, G Pandini, L Sciacca… - Endocrine …, 2009 - academic.oup.com
In mammals, the insulin receptor (IR) gene has acquired an additional exon, exon 11. This
exon may be skipped in a developmental and tissue-specific manner. The IR, therefore …

Insulin, insulin receptors, and cancer

R Vigneri, ID Goldfine, L Frittitta - Journal of endocrinological investigation, 2016 - Springer
Insulin is a major regulator of cell metabolism but, in addition, is also a growth factor. Insulin
effects in target cells are mediated by the insulin receptor (IR), a transmembrane protein with …

Performance of contrast-enhanced ultrasound in thyroid nodules: review of current state and future perspectives

M Radzina, M Ratniece, DS Putrins, L Saule… - Cancers, 2021 - mdpi.com
Simple Summary Ultrasound has been used as baseline imaging for thyroid nodules for
decades; nevertheless, no single feature is sensitive or specific enough to exclude or …

Adipose tissue, obesity and adiponectin: role in endocrine cancer risk

A Tumminia, F Vinciguerra, M Parisi… - International journal of …, 2019 - mdpi.com
Adipose tissue has been recognized as a complex organ with endocrine and metabolic
roles. The excess of fat mass, as occurs during overweight and obesity states, alters the …

Effects of honey and its mechanisms of action on the development and progression of cancer

OO Erejuwa, SA Sulaiman, MSA Wahab - Molecules, 2014 - mdpi.com
Honey is a natural product known for its varied biological or pharmacological activities—
ranging from anti-inflammatory, antioxidant, antibacterial, antihypertensive to hypoglycemic …

A new risk factor indicator for papillary thyroid cancer based on immune infiltration

Z Yang, X Wei, Y Pan, J Xu, Y Si, Z Min, B Yu - Cell death & disease, 2021 - nature.com
Increasing evidence has indicated a close association between immune infiltration in cancer
and clinical outcomes. However, related research in thyroid cancer is still deficient. Our …

The role of insulin receptors and IGF-I receptors in cancer and other diseases

F Frasca, G Pandini, L Sciacca, V Pezzino… - … of physiology and …, 2008 - Taylor & Francis
There is evidence, both in vitro and in vivo, that receptor tyrosine kinases play a key role in
the formation and progression of human cancer. In particular, the insulin-like growth factor …