Merosin-deficient congenital muscular dystrophy type 1A (MDC1A) is a lethal muscle-
wasting disease that is caused by mutations in the LAMA2 gene, resulting in the loss of …

Background and purpose: Duchenne muscular dystrophy (DMD) is a lethal progressive
pediatric muscle disorder and genetically inherited as an X-linked disease that caused by …

MuSK antibody-positive myasthenia gravis (MuSK-MG) accounts for 5 to 15% of
autoimmune MG. MuSK and LRP4 are coreceptors for agrin in the signaling pathway that …

Duchenne muscular dystrophy (DMD), an X-linked disorder caused by loss-of-function
mutations in the dystrophin gene, is characterized by progressive muscle degeneration and …

The extracellular matrix (ECM) provides a solid scaffold and signals to cells through ECM
receptors. The cell–matrix interactions are crucial for normal biological processes and when …

Background and purpose: Duchenne muscular dystrophy (DMD), a lethal X-linked recessive
muscle dystrophy, is resulted in by different mutations including mostly frame-shifting gross …

Skeletal muscle is a highly specialized, postmitotic tissue that must withstand chronic
mechanical and physiological stress throughout life to maintain proper contractile function …

The receptor tyrosine kinase MuSK is indispensable for nerve-muscle synapse formation
and maintenance. MuSK is necessary for prepatterning of the endplate zone anlage and as …

Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder characterized by
progressive muscle degeneration. Mutations in the DMD gene result in the absence of …

Chondroitin sulfate (CS) is a ubiquitous glycosaminoglycan covalently attached to the core
proteins of cell surface, extracellular, and intracellular proteoglycans. The multistep and …