Duchenne muscular dystrophy is typically diagnosed in the preschool years because of
locomotor defects, indicative of muscle damage. Thus, effective therapies must be able to …

Utrophin upregulation is considered a promising therapeutic strategy for Duchenne
muscular dystrophy (DMD). A number of microRNAs (miRNAs) post-transcriptionally …

Duchenne muscular dystrophy (DMD) is an X-linked human disorder in which absence of
the protein dystrophin causes degeneration of skeletal and cardiac muscle. For the sake of …

Duchenne muscular dystrophy is a lethal X-linked muscle disease affecting 1/3500 live male
birth. It results from defects in the subsarcolemmal protein dystrophin, a component of the …

The extracellular matrix (ECM) plays key roles in normal and diseased skeletal and cardiac
muscle. In healthy muscle the ECM is essential for transmitting contractile force, maintaining …

Muscular dystrophy is defined as the progressive wasting of skeletal muscles that is caused
by inherited or spontaneous genetic mutations. Next‐generation sequencing has greatly …

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by
mutations in the dystrophin gene. DMD boys are wheelchair-bound around 12 years and …

Background Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin
gene and afflicts skeletal and cardiac muscles. Previous studies showed that DMD is …

Myogenesis consists of a highly organized and regulated sequence of cellular processes
aimed at forming or repairing muscle tissue. Several processes occur during myogenesis …

Purification of the proteins associated with dystrophin, the gene product responsible for
Duchenne muscular dystrophy, led to the discovery of the dystrophin-glycoprotein complex …