Among diseases affecting skeletal muscle, muscular dystrophy is one of the most
devastating and complex disorders. The term 'muscular dystrophy'refers to a heterogeneous …

Proteoglycans (PGs), which have glycosaminoglycan chains attached to their protein cores,
are essential for maintaining the morphology and function of healthy body tissues …

Duchenne muscular dystrophy (DMD) is a devastating disease that dramatically decreases
the lifespan and abilities of affected young people. The primary molecular cause of the …

Several reports have previously highlighted the potential role of miR-206 in the post-
transcriptional downregulation of utrophin A in cultured cells. Along those lines, we recently …

DMD is a devastatingly progressive muscle wasting disorder of childhood that significantly
shortens life expectancy. Despite efforts to develop an effective therapy that dates back over …

Duchenne muscular dystrophy (DMD) is a severe genetic disorder caused by mutations in
the DMD gene. Absence of dystrophin protein leads to progressive degradation of skeletal …

Duchenne muscular dystrophy (DMD) is a devastating muscle disease caused by loss-of-
function mutations in DMD encoding dystrophin. No rational therapy is currently available …

Extracellular matrix (ECM) myopathies and muscular dystrophies are a group of genetic
diseases caused by mutations in genes encoding proteins that provide critical links between …

Ullrich congenital muscular dystrophy (UCMD), caused by collagen VI deficiency, is a
common congenital muscular dystrophy. At present, the role of collagen VI in muscle and the …

Duchenne muscular dystrophy (DMD) is caused by defects in the DMD gene and results in
progressive wasting of skeletal and cardiac muscle due to an absence of functional …