Microneedles invade skin tissue in a minimally invasive manner, with a small traumatic
surface and slight pain. There is growing interest in the potential application of microneedle …

As drug delivery devices, microneedles are used widely in the local administration of various
drugs. Such drug-loaded microneedles are minimally invasive, almost painless, and have …

Parkinson's disease (PD) is a debilitating neurodegenerative disease primarily impacting
neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a …

Microneedles have garnered considerable attention over the years as a versatile
pharmaceutical platform that could be leveraged to deliver drugs into and across the skin. In …

The various kinds of nanocarriers (NCs) have been explored for the delivery of therapeutics
designed for the management of skin manifestations. The NCs are considered as one of the …

Microneedles (MNs) have been widely applied in transdermal drug delivery owing to their
minimal invasiveness, safety, stability, and ease of administration, which is a promising tool …

ABSTRACT Introduction Microneedles (MNs) have emerged as a promising tool for various
therapeutic and diagnostic applications. While MNs have been prominently used for …

Neurological disorders, including brain injury, brain tumors, and neurodegenerative
diseases, rank as the second leading cause of death worldwide. Exploring effective new …

Obesity, characterized by excessive storage of lipids, has become a global pandemic with
high incidence levels, and its forecast is not encouraging. Currently, there are different …

The purpose of this work is to demonstrate the fabrication process for cleanroom-free solid
metal microneedles and perform quantification of insertion profiles. Metal microneedles …