Multiple biological, synthetic and hybrid polymers are used for multiple medical applications.
A wide range of different polymers is available, and they have further the advantage to be …

The existence of blood–brain barrier (BBB) hampers the effective treatment of central
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …

Glycosaminoglycans (GAGs) govern important functional characteristics of the extracellular
matrix (ECM) in living tissues. Incorporation of GAGs into biomaterials opens up new routes …

With the brain's limited capacity for repair there is a need for new and innovative therapies to
promote regeneration. Stem/progenitor cell transplantation has received increasing …

The catechol plays a variety of important roles in biological processes, prompting
researchers to include them in the design of biomimetic biomedical materials. The low …

Background: Parkinson's disease (PD) is the second most common age-related
neurodegenerative disorder. Levodopa (L-DOPA) remains the gold-standard drug available …

The blood–brain barrier (BBB) is considered as the most challenging barrier in brain drug
delivery. Indeed, there is a definite link between the BBB integrity defects and central …

Undoubtedly the applications of polymers are rapidly evolving. Technology is continually
changing and quickly advancing as polymers are needed to solve a variety of day-to-day …

The brain is a complex 3-dimensional structure, the organization of which provides a local
environment that directly influences the survival, proliferation, differentiation, migration, and …

Introduction: Intranasal drug delivery is a largely unexplored, promising approach for the
treatment of various neurological disorders. However, due to the challenging constraints …