Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

Obstacles and opportunities in a forward vision for cancer nanomedicine

I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

RNAi-based therapeutics and tumor targeted delivery in cancer

G Kara, GA Calin, B Ozpolat - Advanced drug delivery reviews, 2022 - Elsevier
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …

[HTML][HTML] Manganese ferrite (MnFe2O4) nanostructures for cancer theranostics

CR Kalaiselvan, SS Laha, SB Somvanshi… - Coordination Chemistry …, 2022 - Elsevier
Over the past decade, transition metal-based ferrite nanostructures, displaying MFe 2 O 4
stoichiometry (M 2+ cations, eg, Mn, Co, Ni and Zn), have been devised and examined …

Understanding ligand-protected noble metal nanoclusters at work

MF Matus, H Häkkinen - Nature Reviews Materials, 2023 - nature.com
Ligand-protected noble metal nanoclusters, commonly termed 'monolayer-protected metal
clusters'(MPCs), comprise a common set of structures with an inorganic core stabilized by an …

The exit of nanoparticles from solid tumours

LNM Nguyen, ZP Lin, S Sindhwani, P MacMillan… - Nature Materials, 2023 - nature.com
Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …

Metallodrugs in cancer nanomedicine

Q Peña, A Wang, O Zaremba, Y Shi… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

[HTML][HTML] Development of pharmaceutical nanomedicines: from the bench to the market

AA Halwani - Pharmaceutics, 2022 - mdpi.com
Nanotechnology plays a significant role in the field of medicine and in drug delivery, mainly
due to the major limitations affecting the conventional pharmaceutical agents, and older …

[HTML][HTML] Nanoparticles in clinical translation for cancer therapy

D Mundekkad, WC Cho - International journal of molecular sciences, 2022 - mdpi.com
The advent of cancer therapeutics brought a paradigm shift from conventional therapy to
precision medicine. The new therapeutic modalities accomplished through the properties of …

[HTML][HTML] Delivering the power of nanomedicine to patients today

M Germain, F Caputo, S Metcalfe, G Tosi… - Journal of Controlled …, 2020 - Elsevier
The situation of the COVID-19 pandemic reminds us that we permanently need high-value
flexible solutions to urgent clinical needs including simplified diagnostic technologies …