Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …

Sepsis is one of the leading causes of mortality among critically ill patients globally.
According to WHO report 2018, it is estimated to affect beyond 30 million people worldwide …

Variation in the time interval between consecutive R wave peaks of the QRS complex has
long been recognised. Measurement of this RR interval is used to derive heart rate …

Sepsis, the syndrome of infection complicated by acute organ dysfunction, is a serious and
growing global problem, which not only leads to enormous economic losses but also …

Neutrophils are peripheral immune cells that represent the first recruited innate immune
defense against infections and tissue injury. However, these cells can also induce …

Background: Fucoxanthin (FX), a xanthophyll pigment which occurs in marine brown algae
with remarkable biological properties, has been proven to be safe for consumption by …

Recent evidence has suggested that the carotid bodies might act as immunological sensors,
detecting pro-inflammatory mediators and signalling to the central nervous system, which, in …

Mesenchymal stromal cells (MSCs) have been considered a promising alternative for
treatment of acute respiratory distress syndrome (ARDS). However, there is significant …

Inflammation and other immune responses are involved in the variety of diseases and
disorders. The acute response to endotoxemia includes activation of innate immune …

Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by
the hypothalamus. The main biological actions of orexins, focused on the central nervous …