Mechanisms of thrombosis in obesity

IO Blokhin, SR Lentz - Current opinion in hematology, 2013 - journals.lww.com
Obesity-driven chronic inflammation and impaired fibrinolysis appear to be major effector
mechanisms of thrombosis in obesity. The proinflammatory and hypofibrinolytic effects of …

Adipokines: a link between obesity and dementia?

AJ Kiliaan, IAC Arnoldussen, DR Gustafson - The Lancet Neurology, 2014 - thelancet.com
Being overweight or obese, as measured with body-mass index or central adiposity (waist
circumference), and the trajectory of body-mass index over the life course have been …

Obesity and dementia: adipokines interact with the brain

IAC Arnoldussen, AJ Kiliaan, DR Gustafson - European …, 2014 - Elsevier
Obesity is a pandemic and a serious global health concern. Obesity is a risk factor for
multiple conditions and contributes to multi-morbidities, resulting in increased health costs …

Obesity: physiologic changes and implications for preoperative management

VE Ortiz, J Kwo - BMC anesthesiology, 2015 - Springer
The proportion of patients defined as obese continues to grow in many westernized nations,
particularly the United States (USA). This trend has shifted the perioperative management of …

Cardiovascular risk factors in children with obesity, preventive diagnostics and possible interventions

M Močnik, N Marčun Varda - Metabolites, 2021 - mdpi.com
The increasing burden of obesity plays an essential role in increased cardiovascular
morbidity and mortality. The effects of obesity on the cardiovascular system have also been …

Biomarkers for cardiovascular risk in children

JA Canas, S Sweeten… - Current opinion in …, 2013 - journals.lww.com
Associations between biomarkers and noninvasive measures of early atherosclerosis in
children continue to emerge and several biomarkers appear to be promising. At present …

Tissue factor as a mediator of coagulation and signaling in cancer and chronic inflammation

C Graf, W Ruf - Thrombosis research, 2018 - Elsevier
Thrombosis is frequently diagnosed as a first symptom in tumor patients and the clinical
management of hypercoagulability in cancer patients remains challenging due to …

Age-and BMI-associated expression of angiogenic factors in white adipose tissue of children

N Gaebler, B Haggenmüller, M Kapapa… - International journal of …, 2019 - mdpi.com
The growth of adipose tissue and its vasculature are tightly associated. Angiogenic factors
have been linked to obesity, yet little is known about their expression during early childhood …

Impact of obesity on endotoxin-induced disseminated intravascular coagulation

T Duburcq, A Tournoys, V Gnemmi, T Hubert, V Gmyr… - Shock, 2015 - journals.lww.com
An early activation of coagulation and fibrinolysis occurs during sepsis, leading to the
syndrome of disseminated intravascular coagulation (DIC). Obesity has been demonstrated …

Markers of platelet activation are increased in adolescents with type 2 diabetes

SJ Israels, A McNicol, HJ Dean, F Cognasse… - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE In adults with diabetes, in vivo platelet activation is a marker for atherosclerosis
and cardiovascular disease (CVD). This pilot study investigated whether adolescents with …