Tendinopathy: pathophysiology, therapeutic options, and role of nutraceutics. A narrative literature review

C Loiacono, S Palermi, B Massa, I Belviso, V Romano… - Medicina, 2019 - mdpi.com
Tendinopathies are very common in general population and a huge number of tendon-
related procedures take place annually worldwide, with significant socio-economic …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Therapeutic efficacy of bromelain in alveolar ridge preservation

G Chisci, L Fredianelli - Antibiotics, 2022 - mdpi.com
Most of research in regenerative oral surgery describes materials or techniques for
increasing volumetric results for implant-supported prosthesis. The use of bio-materials in …

Bromelain-loaded silver nanoparticles: formulation, characterization and biological activity

F Gheisari, SR Kasaee, P Mohamadian… - Inorganic Chemistry …, 2024 - Elsevier
Bromelain (BL), a type of proteolytic enzymes from Ananas comosus (pineapple), has a
variety of therapeutic potentials; nevertheless, its low bioavailability has restricted the clinical …

Melanin and melanin-like hybrid materials in regenerative medicine

C Cavallini, G Vitiello, B Adinolfi, B Silvestri… - Nanomaterials, 2020 - mdpi.com
Melanins are a group of dark insoluble pigments found widespread in nature. In mammals,
the brown-black eumelanins and the reddish-yellow pheomelanins are the main …

Nutrition in wound healing: investigation of the molecular mechanisms, a narrative review

B Palmieri, M Vadalà, C Laurino - Journal of Wound Care, 2019 - magonlinelibrary.com
Nutrition can be outlined in terms of epigenetic signals influencing each of the wound
healing steps (haemostasis, inflammatory, proliferative and remodelling phase). Specific …

Bromelain‐based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long‐term outcomes

Y Shoham, K Gasteratos, AJ Singer… - International Wound …, 2023 - Wiley Online Library
Abstract In 2012 the European Medicines Agency approved a pineapple stem‐derived
Bromelain‐based debridement concentrate of proteolytic enzymes (NexoBrid®, MediWound …

Bacterial nanocellulose loaded with bromelain: assessment of antimicrobial, antioxidant and physical-chemical properties

JA Ataide, NM de Carvalho, MA Rebelo, MV Chaud… - Scientific reports, 2017 - nature.com
Bacterial nanocellulose (BNC) has desirable properties for wound healing such as high
purity, good shape retention, and high water binding capacity. Bromelain is a protease found …

Pineapple waste-based-biorefinery for sustainable generation of value-added products

P Dhar, C Nickhil, R Pandiselvam, SC Deka - Biomass Conversion and …, 2023 - Springer
Pineapple is indeed a non-climacteric tropical fruit that is known for its juiciness, pleasant
aroma, flavour, and various health-beneficial compounds. The pineapple industry has …

Investigation of antibacterial activity and wound healing promotion properties induced by bromelain-loaded silver nanoparticles

MA Ashij, HS Al-Shmgani, GM Sulaiman… - Plasmonics, 2023 - Springer
With the demand for better chronic wound care, the clinical problem of managing wound
infections has already reached a critical level. Therefore, the development of novel antibiotic …