Cerebral palsy, which occurs in two to three out of 1,000 live births, has multiple etiologies
resulting in brain injury that affects movement, posture, and balance. The movement …

Osteogenesis imperfecta (OI) is a monogenic bone fragility disorder that usually is caused
by mutations in one of the two genes coding for collagen type I alpha chains, COL1A1 or …

This narrative review discusses several aspects of the management of osteoporosis in
patients under 50 years of age. Peak bone mass is genetically determined but can also be …

Childhood, adolescent, and young adult cancer survivors are at increased risk of reduced
bone mineral density. Clinical practice surveillance guidelines are important for timely …

Background Osteoporosis incidence in children is increasing due to the increased survival
rate of patients suffering from chronic diseases and the increased use of drugs that can …

Osteoporosis is a condition of increased bone fragility associated with fractures. Apart from
primary genetic osteoporotic conditions, secondary osteoporosis in children is being …

Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder
primarily characterised by skeletal deformity and fragility, and an array of secondary …

Objective: To systematically analyze the supporting evidence, drug information, and the type
of off-label drug use in recommendations on off-label drug use in pediatric guidelines …

Osteoporosis in children differs from adults in terms of definition, diagnosis, monitoring and
treatment options. Primary osteoporosis comprises primarily of osteogenesis imperfecta (OI) …

The Brazilian guidelines for prevention and treatment of glucocorticoid-induced
osteoporosis were updated and important topics were included such as assessment of risk …