The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

Typhoid fever control in the 21st century: where are we now? : Current Opinion in Infectious
Diseases Typhoid fever control in the 21st century: where are we now? : Current Opinion in …

Background Typhoid fever is a substantial public health problem in Africa, yet there are few
clinical trials of typhoid conjugate vaccine (TCV). We assessed immunogenicity and safety of …

The disease burden of typhoid fever remains high in endemic areas in Asia and Africa,
especially in children. Recent clinical trials conducted by the Typhoid Vaccine Acceleration …

Background Randomised controlled trials of typhoid conjugate vaccines among children in
Africa and Asia have shown high short-term efficacy. Data on the durability of protection …

Typhoid fever is a significant global health problem that impacts people living in areas
without access to clean water and sanitation. However, collaborative international …

Quick and accurate detection of neutralizing antibodies (nAbs) against yellow fever is
essential in serodiagnosis during outbreaks for surveillance and to evaluate vaccine efficacy …

Typhoid fever is a serious disease that disproportionately impacts children in low-resource
settings in sub-Saharan Africa, South and Southeast Asia, and the Western Pacific. The …

We evaluated safety, reactogenicity, and immunogenicity when the WHO-prequalified single-
dose Typhoid Vi-polysaccharide conjugate vaccine, Typbar-TCV®, was administered …

Background Vaccination plays a critical role in mitigating the burden associated with yellow
fever (YF). However, there is a lack of comprehensive evidence on the humoral response to …