Important flavonoids and their role as a therapeutic agent

A Ullah, S Munir, SL Badshah, N Khan, L Ghani… - Molecules, 2020 - mdpi.com
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …

Chitosan/Hyaluronic acid/Alginate and an assorted polymers loaded with honey, plant, and marine compounds for progressive wound healing—Know-how

M Prasathkumar, S Sadhasivam - International Journal of Biological …, 2021 - Elsevier
Biomaterials are being extensively used in regenerative medicine including tissue
engineering applications, as these enhance tissue development, repair, and help in the …

An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study

S Das, S Sarmah, S Lyndem… - Journal of Biomolecular …, 2021 - Taylor & Francis
A new strain of a novel infectious disease affecting millions of people, caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been declared as a …

Mechanism of ferroptosis and its role in type 2 diabetes mellitus

W Sha, F Hu, Y Xi, Y Chu, S Bu - Journal of diabetes research, 2021 - Wiley Online Library
Ferroptosis is a novel form of nonapoptotic regulated cell death (RCD). It features iron‐
dependent lipid peroxide accumulation accompanied by inadequate redox enzymes …

[HTML][HTML] Molecular docking, validation, dynamics simulations, and pharmacokinetic prediction of natural compounds against the SARS-CoV-2 main-protease

C Shivanika, D Kumar, V Ragunathan… - … structure & dynamics, 2020 - ncbi.nlm.nih.gov
The study aims to evaluate the potency of two hundred natural antiviral phytocompounds
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …

[HTML][HTML] Mechanistic insights and perspectives involved in neuroprotective action of quercetin

AK Grewal, TG Singh, D Sharma, V Sharma… - Biomedicine & …, 2021 - Elsevier
Neurodegenerative diseases (NDDs) are the primary cause of disabilities in the elderly
people. Growing evidence indicates that oxidative stress, mitochondrial dysfunction …

An intriguing approach toward antibacterial activity of green synthesized Rutin-templated mesoporous silica nanoparticles decorated with nanosilver

M Abbasi, R Gholizadeh, SR Kasaee, A Vaez… - Scientific reports, 2023 - nature.com
In recent years, mesoporous silica nanoparticles (MSNs) have been applied in various
biomedicine fields like bioimaging, drug delivery, and antibacterial alternatives. MSNs could …

Rutin: A flavonoid as an effective sensitizer for anticancer therapy; insights into multifaceted mechanisms and applicability for combination therapy

A Satari, S Ghasemi, S Habtemariam… - Evidence‐Based …, 2021 - Wiley Online Library
Rutin is a unique antioxidant flavonoid that is mainly found in fruit, vegetables, cereals, and
many other plant‐based human diets. This review aims to highlight the in vitro anticancer …

[PDF][PDF] Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols: an in silico strategy unveils a hope against CORONA

S Adem, V Eyupoglu, I Sarfraz, A Rasul, M Ali - Preprints, 2020 - academia.edu
COVID-19, a rapidly spreading new strain of coronavirus, has affected more than 150
countries and received worldwide attention. The lack of efficacious drugs or vaccines …

Neuroprotective effects of quercetin in Alzheimer's disease

H Khan, H Ullah, M Aschner, WS Cheang, EK Akkol - Biomolecules, 2019 - mdpi.com
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. It is widely distributed among plants and found commonly in daily diets …