The critical role of primary care clinicians (PCCs) in Alzheimer's disease (AD) prevention,
diagnosis and management must evolve as new treatment paradigms and disease …

A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …

Objective To identify an optimal lifestyle profile to protect against memory loss in older
individuals. Design Population based, prospective cohort study. Setting Participants from …

Objective To determine the impact of lifestyle factors on life expectancy lived with and
without Alzheimer's dementia. Design Prospective cohort study. Setting The Chicago Health …

Objective To optimise dementia prevention strategies, we must understand the complex
relationships between lifestyle behaviours, frailty and genetics. Methods We explored …

Background Diet, the gut microbiota, and microRNAs (miRNAs) have been recognized as
factors possibly influencing the pathogenesis of Alzheimer's disease. However, the …

Background: MIND diet, a hybrid of the Mediterranean diet and the Dietary Approaches to
Stop Hypertension diet, is associated with a slower cognitive decline and lower risk of …

A robust preclinical disease model is a primary requirement to understand the underlying
mechanisms, signaling pathways, and drug screening for human diseases. Although various …

Alzheimer's dementia is a pathologically heterogeneous and biologically multilayered
disease. Recent studies and exercises in nomenclature reveal shortcomings in existing …

At present, Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two highly
prevalent disorders worldwide, especially among elderly individuals. T2DM appears to be …