Suppressive effects of isofraxidin on depressive-like behaviors induced by chronic unpredictable mild stress in mice

X Wu, J Gu, Z Zou, M Yu, C Zhang, Q Xiao, X Chen… - Brain Sciences, 2022 - mdpi.com
Isofraxidin is an active component of several traditional and functional plants that have
beneficial properties for neurodegenerative diseases. In this study, we examined whether …

Betanin mitigates scopolamine-induced cognitive impairment by restoring cholinergic function, boosting brain antioxidative status, and increasing BDNF level in the …

BS Thawkar, G Kaur - Fish Physiology and Biochemistry, 2023 - Springer
Betalains obtained from Beta vulgaris (family Caryophyllales) are regularly consumed as
part of the regular diet with medicinal benefits due to antioxidant and anti-inflammatory …

Protective effect of a hydromethanolic extract from Fraxinus excelsior L. bark against a rat model of aluminum chloride-induced Alzheimer's disease: Relevance to its …

A Iranpanah, S Fakhri, G Bahrami, MB Majnooni… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Fraxinus excelsior L.(FE), commonly known as the ash,
belongs to the Oleaceae family and has shown several pharmacological and biological …

DAPK1 mediates cognitive dysfunction and neuronal apoptosis in PSD rats through the ERK/CREB/BDNF signaling pathway

X Zhang, L Fan, L Yang, X Jin, H Liu, H Lei… - Behavioural Brain …, 2024 - Elsevier
Post-stroke depression (PSD) is one of the most common mental sequelae after a stroke and
can damage the brain. Although PSD has garnered increasing attention in recent years, the …

[HTML][HTML] The coumarin component isofraxidin targets the G-protein-coupled receptor S1PR1 to modulate IL-17 signaling and alleviate ulcerative colitis

Y Huang, X Chen, X Liu, C Lin, Y Wang - International …, 2024 - Elsevier
Objective The increasing global prevalence of ulcerative colitis (UC) underscores the
imperative to explore novel therapeutic approaches. Traditional Chinese medicine has …