Depression is a common and serious disorder, characterized by symptoms like anhedonia,
lack of energy, sad mood, low appetite, and sleep disturbances. This disease is very …

Hypothalamic-pituitary adrenal (HPA) axis dysregulation has long been implicated in stress-
related disorders such as major depression and post-traumatic stress disorder …

Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …

Tryptophan (Tryp) is an essential amino acid and the precursor of several neuroactive
compounds within the central nervous system (CNS). Tryp metabolism, the common …

Traumatic brain injury (TBI) has a profound impact on cognitive and mental functioning,
leading to lifelong impairment and significantly diminishing the quality of life for affected …

Psychiatric disorders affect 970 million people worldwide, representing a significant source
of disability. Although the underlying neurobiological traits for these disorders are not fully …

In patients affected by Parkinson's disease (PD), up to 50% of them experience cognitive
changes, and psychiatric disturbances, such as anxiety and depression, often precede the …

The Janus kinase-signal transducer and transcription activator pathway (JAK-STAT) serves
as a cornerstone in cellular signaling, regulating physiological and pathological processes …

Introduction Despite the growing number of different therapeutic options, treatment of
depression is still a challenge. A broader perspective reveals the benefits of bright light …

Important functions of the prefrontal cortex (PFC) are established during early life, when
neurons exhibit enhanced synaptic plasticity and synaptogenesis. This developmental stage …