Latanoprost in the treatment of glaucoma

A Alm - Clinical ophthalmology, 2014 - Taylor & Francis
Prostaglandins are approved by the European Glaucoma Society guidelines as first-line
treatment for glaucoma. This review focuses on latanoprost, an ester prodrug of …

Advances in the noninvasive diagnosis of dry eye disease

L Di Cello, M Pellegrini, A Vagge, M Borselli… - Applied Sciences, 2021 - mdpi.com
Dry eye disease (DED) is a multifactorial disease that represents one of the most common
ophthalmologic conditions encountered in everyday clinical practice. Traditional diagnostic …

Long-term safety and efficacy of latanoprostene bunod 0.024% in Japanese subjects with open-angle glaucoma or ocular hypertension: the JUPITER study

K Kawase, JL Vittitow, RN Weinreb, M Araie… - Advances in …, 2016 - Springer
Introduction Latanoprostene bunod (LBN) is a novel nitric oxide (NO)-donating
prostaglandin F2α analog. We evaluated the long-term safety and intraocular pressure (IOP) …

Open-angle glaucoma: burden of illness, current therapies, and the management of nocturnal IOP variation

A Sheybani, R Scott, TW Samuelson… - Ophthalmology and …, 2020 - Springer
Glaucoma is a chronic, debilitating disease and a leading cause of global blindness.
Despite treatment efforts, 10% of patients demonstrate loss of vision. In the US,> 80% of …

Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium

L David Waterbury, D Silliman… - Current medical research …, 2006 - Taylor & Francis
Objective: To compare the cyclooxygenase (COX) activity and anti-inflammatory effects of
the nonsteroidal anti-inflammatory drugs (NSAIDs) ketorolac tromethamine (ketorolac) and …

Update on the role of alpha-agonists in glaucoma management

S Arthur, LB Cantor - Experimental Eye Research, 2011 - Elsevier
Glaucoma is the second most common cause of world blindness (following cataract) with
estimated cases reaching 79.6 million by 2020. Although the etiology of glaucoma is multi …

Epigallocatechin gallate, an active ingredient from green tea, attenuates damaging influences to the retina caused by ischemia/reperfusion

B Zhang, R Safa, D Rusciano, NN Osborne - Brain Research, 2007 - Elsevier
The aim of this study was to examine whether the antioxidant epigallocatechin gallate
(EGCG), a catechin-base flavonoid derived from green tea protects retina neurones in situ …

The suprachoroidal pathway: a new drug delivery route to the back of the eye

UDJP Rai, SA Young, TR Thrimawithana… - Drug discovery today, 2015 - Elsevier
Highlights•Drug injection into the suprachoroidal space using microneedles offers direct
access to the choroid and retina.•It is a promising alternative to intravitreal injection.•Benefits …

The flavonoid baicalin counteracts ischemic and oxidative insults to retinal cells and lipid peroxidation to brain membranes

SH Jung, KD Kang, D Ji, RJ Fawcett, R Safa… - Neurochemistry …, 2008 - Elsevier
The purpose of the present study was to determine whether the flavonoid, baicalin is
effective at blunting the negative influence of ischemia/reperfusion to the rat retina in situ …

Recent advances in pharmacotherapy of glaucoma

SK Gupta, ND Galpalli, SS Agrawal… - Indian journal of …, 2008 - journals.lww.com
Glaucoma is a slow progressive degeneration of the retinal ganglion cells (RGCs) and the
optic nerve axons, leading to irreversible blindness if left undiagnosed and untreated …