Targeting aging mechanisms: pharmacological perspectives
A Moskalev, Z Guvatova, IDA Lopes, CW Beckett… - Trends in Endocrinology …, 2022 - cell.com
Geroprotectors slow down aging and promote healthy longevity in model animals. Although
hundreds of compounds have been shown to extend the life of laboratory model organisms …
hundreds of compounds have been shown to extend the life of laboratory model organisms …
Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
Efficacy and safety of nintedanib in a Greek multicentre idiopathic pulmonary fibrosis registry: a retrospective, observational, cohort study
K Antoniou, K Markopoulou, A Tzouvelekis… - ERJ open …, 2020 - Eur Respiratory Soc
Nintedanib is a tyrosine kinase inhibitor approved for the treatment of idiopathic pulmonary
fibrosis (IPF). In a retrospective, real-world study across seven Greek hospitals, we …
fibrosis (IPF). In a retrospective, real-world study across seven Greek hospitals, we …
Anti‐fibrotic effects of different sources of MSC in bleomycin‐induced lung fibrosis in C57BL6 male mice
S Periera‐Simon, X Xia, P Catanuto, R Coronado… - …, 2021 - Wiley Online Library
Background and objective IPF is a fatal and debilitating lung disorder increasing in
incidence worldwide. To date, two approved treatments only slow disease progression, have …
incidence worldwide. To date, two approved treatments only slow disease progression, have …
Transcriptome analysis of IPF fibroblastic foci identifies key pathways involved in fibrogenesis
D Guillotin, AR Taylor, M Platé, PF Mercer, LM Edwards… - Thorax, 2021 - thorax.bmj.com
Introduction Fibroblastic foci represent the cardinal pathogenic lesion in idiopathic
pulmonary fibrosis (IPF) and comprise activated fibroblasts and myofibroblasts, the key …
pulmonary fibrosis (IPF) and comprise activated fibroblasts and myofibroblasts, the key …
Recent Advances (2015–2020) in Drug Discovery for Attenuation of Pulmonary Fibrosis and COPD
A Dorababu, M Maraswami - Molecules, 2023 - mdpi.com
A condition of scarring of lung tissue due to a wide range of causes (such as environmental
pollution, cigarette smoking (CS), lung diseases, some medications, etc.) has been reported …
pollution, cigarette smoking (CS), lung diseases, some medications, etc.) has been reported …
Cell therapy for idiopathic pulmonary fibrosis: rationale and progress to date
P Ntolios, P Steiropoulos, G Karpathiou, S Anevlavis… - BioDrugs, 2020 - Springer
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive
lung scarring due to unknown injurious stimuli ultimately leading to respiratory failure …
lung scarring due to unknown injurious stimuli ultimately leading to respiratory failure …
Yiqi Yangyin Huoxue Method in Treating IdiopathicPulmonary Fibrosis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
M Zhou, C Ye, Q Liang, Q Pei, F Xu… - … and Alternative Medicine, 2020 - Wiley Online Library
Objective. Idiopathic pulmonary fibrosis (IPF) is a common respiratory disease that can lead
to respiratory failure in severe condition. Despite notable advances in its treatment, some …
to respiratory failure in severe condition. Despite notable advances in its treatment, some …
Exploring therapeutic targets for molecular therapy of idiopathic pulmonary fibrosis
Y Li, C Jiang, W Zhu, S Lu, H Yu, L Meng - Science Progress, 2024 - journals.sagepub.com
Idiopathic pulmonary fibrosis is a chronic and progressive interstitial lung disease with a
poor prognosis. Idiopathic pulmonary fibrosis is characterized by repeated alveolar …
poor prognosis. Idiopathic pulmonary fibrosis is characterized by repeated alveolar …
Potential function and molecular mechanism of circRNAs involved in idiopathic pulmonary fibrosis
F Li, H Wang, H Tao, F Wu, D Wang, Y Wan - 2020 - researchsquare.com
Background: Recent studies have found a regulatory role of circular RNAs (circRNAs) in the
pathogenesis of idiopathic pulmonary brosis (IPF). However, the function and underlying …
pathogenesis of idiopathic pulmonary brosis (IPF). However, the function and underlying …